409-03-003 / 271-01-039 ISMRM Abstract

UTE-MRI Detects Increased Fat Deposition in Cortical Pores of Diabetic Bones

Primary: Musculoskeletal - Bone

Secondary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others

409-03-003 · Quantitative Imaging: Applications · Tuesday, 12 May, 1:40 PM–3:30 PM · Meeting Room 2.40

271-01-039 · ISMRM AMPC Selected Posters · Sunday, 10 May, 7:00 AM–2:00 PM · Traditional Posters

Keywords: Diabetes Bone Ultra-short Echo Time (UTE) Fat-water MR quantification

Accepted

Soo Hyun Shin ¹, Qingbo Tang^1,2, Saeed Jerban¹, Eric Y Chang^1,2, Jeremy H Pettus¹, Gina N Woods¹, Yajun Ma¹, Jiang Du^1,2

¹University of California, Berkeley, United States of America

²Radiology Service, VA San Diego Healthcare System, La Jolla, California, San Diego, United States of America

Presenting Author: Soo Hyun Shin

Synopsis

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References

1. Saito M et al. Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int. 2010;21:195-214.

2. Patsch et al., Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures. JBMR. 2013;28:313-324.

3. Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis. Osteoporos Int. 2007;18:427-444.

4. Samelson et al., Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR‐pQCT Study. JBMR. 2018;33:54-62.

5. He et al., Micron-resolution Imaging of Cortical Bone under 14 T Ultrahigh Magnetic Field. Adv Sci. 2023;10:2300959.

6. Lu et al., Three-dimensional ultrashort echo time imaging with tricomponent analysis for human cortical bone. Magn Reson Med. 2019;82:348-355.

7. Napoli et al., Mechanisms of diabetes mellitus-induced bone fragility. Nat Rev Endocrinol. 2017;13:208-219.

8. Shin et al., Spectrally-selective and interleaved water imaging and fat imaging (siWIFI). Magn Reson Med. 2025;93:1556-1567.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/409-03-003