662-02-004 ISMRM Abstract

Reference-locked Evaluation of HyperCEST MRI for Reliable Depolarization Quantification

Primary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI

Secondary: Analysis Methods - Data Processing

662-02-004 · Advances in Chemical Exchange MRI: CEST, APT, and NOE II · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row C

Keywords: CEST MRI HyperCEST Hyperpolarized Xenon-129 MRI Parameter quantification

Accepted

Leif Schröder ^1,2,3, Jabadurai Jayapaul¹

¹Translational Molecular Imaging, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany

²German Cancer Consortium (DKTK), Heidelberg, Germany

³Department of Physics and Astronomy, Ruprecht Karls University Heidelberg, Heidelberg, Germany

Presenting Author: Leif Schröder

Synopsis

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References

1. Jayapaul, J. & Schröder, L. Molecular Sensing with Host Systems for Hyperpolarized 129Xe. Molecules 25, 4627 (2020). doi:10.3390/molecules25204627 [doi]

2. Zaiss, M., Schnurr, M. & Bachert, P. Analytical solution for the depolarization of hyperpolarized nuclei by chemical exchange saturation transfer between free and encapsulated xenon (HyperCEST). J. Chem. Phys. 136, 144106–10 (2012). doi: 10.1063/1.3701178 [doi]

3. Kunth, M., Witte, C. & Schröder, L. Quantitative chemical exchange saturation transfer with hyperpolarized nuclei (qHyper-CEST): Sensing xenon-host exchange dynamics and binding affinities by NMR. J. Chem. Phys. 141, 194202 (2014). doi: 10.1063/1.4901429 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/662-02-004