Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
361-05-008 ISMRM Abstract

Synthetic MRI Combined With Clinical Characteristics for Prediction of Ki-67 Status in Nasopharyngeal Carcinoma

Primary: Acquisition & Reconstruction - Quantitative Imaging: head and neck
Secondary: Analysis Methods - Radiomics
361-05-008 · Quantitative Imaging: Head and Neck I · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row B
Keywords: Nasopharyngeal carcinoma Synthetic magnetic resonance imaging Intratumoral heterogeneity Ki-67
Accepted
Yulin Wang 1, Huanhuan Ren1,2, Daihong Liu1,3,4, Lisha Nie5, Jiuquan Zhang4
1Department of Radiology Chongqing University Cancer Hospital, Chongqing, chongqing, China
2Chongqing University Cancer Hospital, Chongqing, China
3Department of Radiology, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, ChongQing, China
4Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, ChongQing, China
5GE Healthcare, MR Research China, Beijing, China
Presenting Author: Yulin Wang

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References

1. Wong KCW, Hui EP, Lo K-W, et al. Nasopharyngeal carcinoma: an evolving paradigm. Nat Rev Clin Oncol. 2021;18(11):679-695. doi:10.1038/s41571-021-00524-x [doi]
2. Li Y, Yue L, Li Y, Zhang Q, Liang X. Prognostic value of Ki-67 in nasopharyngeal carcinoma: a meta-analysis. Biosci Rep. 2021;41(5)doi:10.1042/BSR20203334 [doi]
3. Zhao L, Chen H, Hu B, Zhang H, Lin Q. Prognostic significance of Ki67 expression and the derived neutrophil-lymphocyte ratio in nasopharyngeal carcinoma. Cancer Manag Res. 2018;10:1919-1926. doi:10.2147/CMAR.S167626 [doi]
4. Zhao Y, Shen L, Huang X, et al. High expression of Ki-67 acts a poor prognosis indicator in locally advanced nasopharyngeal carcinoma. Biochem Biophys Res Commun. 2017;494(1-2):390-396. doi:10.1016/j.bbrc.2017.09.118 [doi]
5. Yang F, Wei H, Li X, et al. Pretreatment synthetic magnetic resonance imaging predicts disease progression in nonmetastatic nasopharyngeal carcinoma after intensity modulation radiation therapy. Insights Imaging. 2023;14(1):59. doi:10.1186/s13244-023-01411-y [doi]
6. Yang F, Li X, Li Y, et al. Histogram analysis of quantitative parameters from synthetic MRI: correlations with prognostic factors in nasopharyngeal carcinoma. Eur Radiol. 2023;33(8):5344-5354. doi:10.1007/s00330-023-09553-9 [doi]
7. Huang W, Zhang Q, Wu G, et al. DCE-MRI quantitative transport mapping for noninvasively detecting hypoxia inducible factor-1α, epidermal growth factor receptor overexpression, and Ki-67 in nasopharyngeal carcinoma patients. Radiother Oncol. 2021;164:146-154. doi:10.1016/j.radonc.2021.09.016 [doi]
8. Ai QYH, Chan AB, Chan AZ, et al. T1rho imaging of head and neck cancer: its association with pathological and immunohistochemical biomarkers in nasopharyngeal carcinoma. Cancer Imaging. 2025;25(1):118. doi:10.1186/s40644-025-00940-7 [doi]

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http://echo.ismrm.org/p/ISMRM2026/361-05-008