Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-05-008 ISMRM Abstract

Mapping pulsatility along the vascular tree using time-encoded arterial spin labeling MRI

Accepted
Maaike van Tol 1, Natalia Petridou2,3, Matthias van Osch1, Lena Vaclavu1
1C.J. Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands
2University Medical Center Utrecht, Utrecht, Netherlands
3Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands
Presenting Author: Maaike van Tol

Synopsis

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References

1. Wagshul ME, Eide PK, Madsen JR. The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility. Fluids Barriers CNS. 2011;8(1):5. doi:10.1186/2045-8118-8-5 [doi]
2. Shi Y, Thrippleton MJ, Marshall I, Wardlaw JM. Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review. Clin Sci (Lond). 2018;132(1):157-171. doi:10.1042/CS20171280 [doi]
3. Pahlavian SH, Wang X, Ma S, et al. Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study. J Cereb Blood Flow Metab. 2021;41(3):670-683. doi:10.1177/0271678X20927101 [doi]
4. Zhao T, Tang J, He Y, Gill NP, Gamez MT, Yan L. Assessing cerebral microvascular pulsatility using flow pulsatile-resolved pseudo-continuous arterial spin labeling MRI. Magnetic Resonance in Medicine. 2025. doi:10.1002/mrm.70004 [doi]
5. Chen C, Barnes RA, Bangen KJ, et al. MVP-VSASL: measuring MicroVascular Pulsatility using velocity-selective arterial spin labeling. Magnetic Resonance in Medicine. 2025;93(4):1516-1534. doi:10.1002/mrm.30370 [doi]
6. Guo F, Zhao C, Shou Q, et al. Assessing cerebral microvascular volumetric pulsatility with high-resolution 4D cerebral blood volume MRI at 7 T. Nat Cardiovasc Res. Published online September 25, 2025:1-15. doi:10.1038/s44161-025-00722-1 [doi]
7. Teeuwisse WM, Schmid S, Ghariq E, Veer IM, van Osch MJP. Time-encoded pseudocontinuous arterial spin labeling: Basic properties and timing strategies for human applications. Magnetic Resonance in Medicine. 2014;72(6):1712-1722. doi:10.1002/mrm.25083 [doi]
8. Ishida S, Kimura H, Isozaki M, et al. Robust arterial transit time and cerebral blood flow estimation using combined acquisition of Hadamard-encoded multi-delay and long-labeled long-delay pseudo-continuous arterial spin labeling: a simulation and in vivo study. NMR in Biomedicine. 2020;33(8):e4319. doi:10.1002/nbm.4319 [doi]

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