Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-06-010 ISMRM Abstract

Effects of Smoking and Asthma on Development of White Matter Hyperintensities and Iron Distribution in the Brain

Primary: Neuro - White Matter
Secondary: Neuro - Other Neurodegeneration
460-06-010 · Imaging the Brain’s Microenvironment: From Glymphatics to Cognition · Tuesday, 12 May, 4:55 PM–5:50 PM · Digital Posters Row A
Keywords: White Matter Hyperintensities Quantitative Susceptibility Mapping (QSM)
Accepted
Eamon K Doyle1,2, Bethany L Sussman3, Hashem Zamanian4, Ash Rodgers5, Matthew T Borzage3,6,7
1Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, United States of America
2Radiology, Children's Hospital Los Angeles, Los Angeles, United States of America
3Pediatrics, Division of Neonatology, Children's Hospital Los Angeles, Los Angeles, United States of America
4The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, United States of America
5Department of Biological Sciences, Dornsife College, University of Southern California, Los Angeles, United States of America
6Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, United States of America
7USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, United States of America
Presenting Author: John C Wood

Synopsis

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References

1. T. Wang, X. Huang, and J. Wang, “Asthma’s effect on brain connectivity and cognitive decline,” Front. Neurol., vol. 13, p. 1065942, Feb. 2023, doi:10.3389/fneur.2022.1065942 [doi]
2. M. Bloomberg, J. Brown, G. D. Gessa, F. Bu, and A. Steptoe, “Cognitive decline before and after mid-to-late-life smoking cessation: a longitudinal analysis of prospective cohort studies from 12 countries,” Lancet Healthy Longev., vol. 6, no. 9, Sept. 2025, doi:10.1016/j.lanhl.2025.100753 [doi]
3. P. Schmidt et al., “An automated tool for detection of FLAIR-hyperintense white-matter lesions in Multiple Sclerosis,” NeuroImage, vol. 59, no. 4, pp. 3774–3783, Feb. 2012, doi:10.1016/j.neuroimage.2011.11.032 [doi]
4. H. Zamanian, E. Doyle, J. Wood, B. Tamrazi, M. Borzage, and S. Erberich, “Clinically Integrated MRI-QSM Analysis & Reporting System to Establish Brain Tissue Iron Levels in Pediatrics,” presented at the 2025 ISMRM & ISMRT Annual Meeting, Honolulu, Hawaii, USA, 2025, p. 2409. doi:10.58530/2025/2409. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-06-010