Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
467-04-005 ISMRM Abstract

S³-MUSIC: Physics-guided Self-Supervised 4D Ferumoxytol-based Steady-State Cardiac MRI Reconstruction with 32× Acceleration

Accepted
Jun Lyu1, Shu-Fu Shih1, Sile Wang1,2, Yuxiao Wu1,2, Takegawa Yoshida1, Fei Han3, Ning Jin4, Xiaoming Bi3, Arash Bedayat1, Kim-Lien Nguyen1,2,5,6, J. Paul Finn1,2,6, Xiaodong Zhong 1,2,6
1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, United States of America
2Department of Bioengineering, University of California Los Angeles, Los Angeles, United States of America
3MR R&D Collaborations, Siemens Medical Solutions USA, Inc, Los Angeles, United States of America
4MR R&D Collaborations, Siemens Medical Solutions USA, Inc, Cleveland, United States of America
5Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, Los Angeles, United States of America
6Physics and Biology in Medicine Graduate Program, University of California Los Angeles, Los Angeles, United States of America
Presenting Author: Xiaodong Zhong

Synopsis

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References

1. Han F, Rapacchi S, Khan S, Ayad I, Salusky I, Gabriel S, Plotnik A, Finn JP, Hu P. Four-dimensional, multiphase, steady-state imaging with contrast enhancement (MUSIC) in the heart: a feasibility study in children. Magn Reson Med 2015;74:1042-1049.
2. Nguyen KL, Ghosh RM, Griffin LM, Yoshida T, Bedayat A, Rigsby CK, Fogel MA, Whitehead KK, Hu P, Finn JP. Four-dimensional Multiphase Steady-State MRI with Ferumoxytol Enhancement: Early Multicenter Feasibility in Pediatric Congenital Heart Disease. Radiology 2021;300:162-173.
3. Finn JP, Shih SF, Nguyen KL, Bedayat A, Yoshida T, Jin N, Han F, Zhong X. Four-dimensional, ferumoxytol-enhanced MUSIC (multi-phase steady-state imaging with contrast) in a single breath-hold: Technical feasibility in structural heart disease. Proc Intl Soc Mag Reson Med 33. 2025.
4. Vishnevskiy, Valery, Jonas Walheim, and Sebastian Kozerke. "Deep variational network for rapid 4D flow MRI reconstruction." Nature Machine Intelligence 2.4 (2020): 228-235.
5. Jacobs, Luuk, et al. "FlowMRI-Net: A Generalizable Self-Supervised 4D Flow MRI Reconstruction Network." Journal of Cardiovascular Magnetic Resonance (2025): 101913.
6. Ma LE, Markl M, Chow K, Huh H, Forman C, Vali A, Greiser A, Carr J, Schnell S, Barker AJ, Jin N. Aortic 4D flow MRI in 2 minutes using compressed sensing, respiratory controlled adaptive k-space reordering, and inline reconstruction. Magn Reson Med 2019;81:3675-3690.

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