Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
369-05-013 ISMRM Abstract

Estimating 129Xe Dissolved-Phase Gas-exchange Dynamics in the Absence of Spectral Separation Using Blind Estimation

Primary: Contrast Mechanisms - Hyperpolarized MR (Gas)
Secondary: Preclinical Animal & in vitro MR - Biomarkers
369-05-013 · Hyperpolarized Gases · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row J
Keywords: Analysis/Processing Dynamic Imaging Pulmonary Imaging Model fitting
Accepted
Yohn Taylor 1, Luis Loza2, Rachel Brady3, Mina Kim3,4, Kai Ruppert2, Geoff J Parker3,4,5,6
1University College London, London, United Kingdom
2Radiology, University of Pennsylvania, Philadelphia, United States of America
3Hawkes Institute, University College London, London, United Kingdom
4Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom
5Bioxydyn Limited, Manchester, United Kingdom
6UCL Hawkes Institute, University College London, London, United Kingdom
Presenting Author: Yohn Taylor

Synopsis

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References

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3. Patz S, Muradyan I, Hrovat MI, Dabaghyan M, Washko GR, Hatabu H, Butler JP. Diffusion of hyperpolarized ¹²⁹Xe in the lung: a simplified model of ¹²⁹Xe septal uptake and experimental results. New J Phys. 2011;13(1):015009. doi:10.1088/1367-2630/13/1/015009 [doi]
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7. Taylor Y, Parker GJM, Kim M, Jimenez-Royo P. A novel compartmental model of ¹²⁹Xe gas exchange using blind estimation of blood concentration. In: Proceedings of the 33rd Annual Meeting of the International Society for Magnetic Resonance in Medicine; 2025; Toronto, Canada.
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9. Loza L, Ruppert K, Chen J, Hamedani H, Ismail MK, Amzajerdian F, et al. Assessing radiation-induced lung injury using a chemical shift imaging-based CSSR technique. In: Am J Respir Crit Care Med. 2024;209:A4494.
10. Zanette B, Stirrat E, Jelveh S, Hope A, Santyr G. Physiological gas exchange mapping of hyperpolarized ¹²⁹Xe using spiral-IDEAL and MOXE in a model of regional radiation-induced lung injury. Med Phys. 2018;45(2):803-816. doi:10.1002/mp.12734 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/369-05-013