Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-01-012 ISMRM Abstract

Optimized susceptibility-weighted MRI for central vein sign detection in the spinal cord at 7T

Primary: Neuro - Spinal Cord
Secondary: Neuro - Multiple Sclerosis
362-01-012 · Neuro Sequences, Applications, and Traveling Phantoms · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row C
Keywords: Data Processing SWI 7 Tesla Ultra high field MRI Spinal cord lesions
Accepted
Aurelien Destruel 1,2, Sarah Demortière1,2,3, Maxime Guye1,2, Jean Pelletier1,2,3, Virginie Callot1,2
1Aix Marseille Univ, Marseille, France
2APHM, Hôpital Universitaire Timone, CEMEREM, Marseille, France
3APHM, Marseille, France
Presenting Author: Aurelien Destruel

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References

1. Sinnecker T, Clarke MA, Meier D, et al. Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in Multiple Sclerosis. JAMA Neurol. 2019;76(12):1446-1456. doi:10.1001/jamaneurol.2019.2478 [doi]
2. Wattjes MP, Ciccarelli O, Reich DS, et al. 2021 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis. The Lancet Neurology. 2021;20(8):653-670. doi:10.1016/S1474-4422(21)00095-8 [doi]
3. Dawson JW. The histology of disseminated sclerosis. Edinburgh Medical Journal. 1916;17(5):311.
4. Tsagkas C, Donadieu M, Sun R, et al. Spinal cord lesions in MS: Insights from combined ultra-high-resolution postmortem MRI and histology. Proceedings of ECTRIMS. 2025.
5. Clarke MA, Witt AA, Robison RK, et al. Cervical spinal cord susceptibility-weighted MRI at 7T: Application to multiple sclerosis. Neuroimage. 2023;284:120460. doi:10.1016/j.neuroimage.2023.120460 [doi]
6. Massire A, Taso M, Besson P, Guye M, Ranjeva JPP, Callot V. High-resolution multi-parametric quantitative magnetic resonance imaging of the human cervical spinal cord at 7T. NeuroImage. 2016. doi:10.1016/j.neuroimage.2016.08.055 [doi]
7. Brainovich V, Sabatini U, Hagberg GE. Advantages of using multiple-echo image combination and asymmetric triangular phase masking in magnetic resonance venography at 3 T. Magn Reson Imaging. 2009;27(1):23-37. doi:10.1016/j.mri.2008.05.006 [doi]
8. Eckstein K, Bachrata B, Hangel G, et al. Improved susceptibility weighted imaging at ultra-high field using bipolar multi-echo acquisition and optimized image processing: CLEAR-SWI. Neuroimage. 2021;237:118175. doi:10.1016/j.neuroimage.2021.118175 [doi]
9. B. Testud, N. Fabiani, S. Demortière, et al. Contribution of the MP2RAGE 7T Sequence in MS Lesions of the Cervical Spinal Cord. Am J Neuroradiol. 2023;44(9):1101. doi:10.3174/ajnr.A7964 [doi]
10. Kreiter DJ, van den Hurk J, Wiggins CJ, Hupperts RMM, Gerlach OHH. Ultra-high field spinal cord MRI in multiple sclerosis: Where are we standing? A literature review. Mult Scler Relat Disord. 2022;57:103436. doi:10.1016/j.msard.2021.103436 [doi]

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http://echo.ismrm.org/p/ISMRM2026/362-01-012