Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
631-03-003 / 631-03-003 ISMRM Abstract

Approaching the Diffusion Short-Time Limit Using a Human Breast Gradient Coil with Ultra-High Gradients

Primary: Diffusion - Diffusion Acquisition
Secondary: Physics & Engineering - New Devices
631-03-003 · Diffusion Acquisition and Reconstruction · Thursday, 14 May, 4:00 PM–5:36 PM · Roof Terrace
631-03-003 · Diffusion Acquisition and Reconstruction · Thursday, 14 May, 4:00 PM–5:36 PM · Roof Terrace
Keywords: Diffusion MRI Time-dependent diffusion MRI Local Gradient Coils
Accepted
Pablo J Jimenez 1,2, Reiner Umathum1, Sebastian Littin3, Feng Jia3, Frederik B Laun4, Mark E Ladd1,2,5, Maxim Zaitsev3, Tristan A Kuder1,2
1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
2Faculty of Physics and Astronomy, University of Heidelberg, Heidelberg, Germany
3University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
4Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany
5Faculty of Medicine, University of Heidelberg, Heidelberg, Germany
Presenting Author: Pablo J Jimenez

Synopsis

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References

1. Park VY, Shin HJ, Kang BJ, Kim MJ, Moon WK, Song SE, Ha SM, et al., Diffusion-Weighted Magnetic Resonance Imaging for Preoperative Evaluation of Patients With Breast Cancer: Protocol of a Prospective, Multicenter, Observational Cohort Study. J Breast Cancer. 2023. DOI: 10.4048/jbc.2023.26.e18 [doi]
2. Ba R, Wang X, Zhang Z, Li, Q, Sun Y, Zhang J, & Wu D. Diffusion-time dependent diffusion MRI: effect of diffusion-time on microstructural mapping and prediction of prognostic features in breast cancer. European Radiology, 33(9), 6226-6237. 2023. DOI: 10.1007/s00330-023-09623-y [doi]
3. Palm T, Wenkel E, Ohlmeyer S, Janka R, Uder M, Weiland E, Bickelhaupt S, Ladd ME, Zaitsev M, Hensel B, Laun FB, et al., Diffusion kurtosis imaging does not improve differentiation performance of breast lesions in a short clinical protocol. Magn Reson Imaging 63:205-216. 2019. DOI: 10.1016/j.mri.2019.08.007 [doi]
4. Kuder, T. A., Bachert, P., Windschuh, J., Laun, F. B, et al. Diffusion pore imaging by hyperpolarized xenon-129 nuclear magnetic resonance. Physical review letters, 111.2. 2013. DOI: https://doi.org/10.1103/PhysRevLett.111.028101 [doi]
5. Jia, F., Littin, S., Amrein, P., Yu, H., Magill, A. W., Kuder, T. A., Zaitsev, M., et al., Design of a high-performance non-linear gradient coil for diffusion weighted MRI of the breast. Journal of Magnetic Resonance (Vol. 331). 2021. DOI: 10.1016/j.jmr.2021.107052 [doi]
6. Jia, F., Littin, S., Amrein, P., Kroboth, S., Yu, H., Magill, A. W., Zaitsev, M., et al., Design of a non-linear human breast diffusion coil, preprint: https://arxiv.org/abs/2012.12813. DOI: https://doi.org/10.48550/arXiv.2012.12813 [doi]
7. Littin, S., Feng Jia, F., Amrein, P. et al., Single channel non-linear breast gradient coil for diffusion encoding. Proc Intl Soc Mag Reson Med. 2020.
8. Bieling S., Ladd M.E, Magill A., et al., Comparative design study of a 3T 1H RF breast coil: quadrature vs. solenoid design. Proc Intl Soc Mag Reson Med. 2019.
9. Jia F., Littin S., Kroboth S., Yu H., Palm T., Laun, F. B, Ladd M.E, and Maxim Zaitsev et al., Design of breast gradient coil with the control of field nonlinearity. Proc Intl Soc Mag Reson Med. 2018.
10. Laun F. B., Demberg K., Nage A. M., Uder M. Kuder T. A. On the Vanishing of the t-term in the Short-Time Expansion of the Diffusion Coefficient for Oscillating Gradients in Diffusion NMR. Frontiers in Physics, 5, 56. 2017. DOI: https://doi.org/10.3389/fphy.2017.00056 [doi]
11. Novikov D. S., Jensen J. H., Helpern J. A., Fieremans, E. Revealing mesoscopic structural universality with diffusion. Proceedings of the National Academy of Sciences, 111(14), 5088-5093. 2014. DOI: 10.1073/pnas.1316944111 [doi]
12. Aggarwal, M., Smith, M. D., & Calabresi, P. A. Diffusion‐time dependence of diffusional kurtosis in the mouse brain. Magnetic resonance in medicine, 84(3), 1564-1578. 2020. DOI: 10.1002/mrm.28189 [doi]

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http://echo.ismrm.org/p/ISMRM2026/631-03-003