Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
503-02-003 ISMRM Abstract

Advanced Diffusion-Weighted Imaging Modeling to Predict Upstaging of Ductal Carcinoma In Situ to Invasive Cancer at Surgery

Primary: Body - Breast
Secondary: Diffusion - Diffusion Modeling
503-02-003 · Body Diffusion MRI · Wednesday, 13 May, 1:40 PM–3:30 PM · Auditorium 1
Keywords: IVIM-DWI DKI Diffusion-weighted MRI Ductal carcinoma in situ Impeded diffusion fraction
Accepted
Debosmita Biswas 1,2, Daniel S Hippe3, Dariya Malyarenko4, Anum Kazerouni1, Isabella Li1, Vivian Youngjean Park5, sara javid6, Mark Kilgore7, Savannah Partridge6, Habib Rahbar1,2
1Radiology, University of Washington, Seattle, United States of America
2Bioengineering, University of Washington, Seattle, United States of America
3Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, United States of America
4University of Michigan, Ann Arbor, United States of America
5Yonsei University College of Medicine, Seoul, Korea, Republic of
6University of Washington, Seattle, United States of America
7Department of Laboratory Medicine and Pathology, University of Washington, Seattle, United States of America
Presenting Author: Debosmita Biswas

Synopsis

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References

1. 1) Javid SH, Kazerouni AS, Hippe DS, Hirano M, Schnuck-Olapo J, Biswas D, Bryant ML, Li I, Xiao J, Kim AG, Guo A, Dontchos B, Kilgore M, Kim J, Partridge SC, Rahbar H. Preoperative MRI to Predict Upstaging of DCIS to Invasive Cancer at Surgery. Ann Surg Oncol. 2025 May;32(5):3234-3243. doi: 10.1245/s10434-024-16837-x. Epub 2025 Jan 28. Erratum in: Ann Surg Oncol. 2025 May;32(5):3350. doi: 10.1245/s10434-025-17029-x. PMID: 39873851. [doi] [pmid]
2. 2) Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986 Nov;161(2):401-7. doi: 10.1148/radiology.161.2.3763909. PMID: 3763909. [doi] [pmid]
3. 3) Jensen JH, Helpern JA. MRI quantification of non-Gaussian water diffusion by kurtosis analysis. NMR Biomed. 2010 Aug;23(7):698-710. doi: 10.1002/nbm.1518. PMID: 20632416; PMCID: PMC2997680. [doi] [pmid]
4. 4) Sigmund EE, Cho GY, Kim S, Finn M, Moccaldi M, Jensen JH, Sodickson DK, Goldberg JD, Formenti S, Moy L. Intravoxel incoherent motion imaging of tumor microenvironment in locally advanced breast cancer. Magn Reson Med. 2011 May;65(5):1437-47. doi: 10.1002/mrm.22740. Epub 2011 Feb 1. PMID: 21287591; PMCID: PMC4692245. [doi] [pmid]
5. 5) Malyarenko DI, Swanson SD, McGarry SD, LaViolette PS, Chenevert TL. The impeded diffusion fraction quantitative imaging assay demonstrated in multi-exponential diffusion phantom and prostate cancer. Magn Reson Med. 2022 Apr;87(4):2053-2062. doi: 10.1002/mrm.29075. Epub 2021 Nov 14. PMID: 34775621; PMCID: PMC8810585. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/503-02-003