562-06-003 ISMRM Abstract

Chemogenetically-Evoked Neurochemical Dynamics and Interhemispheric Metabolic Coupling Probed by ¹H-fMRS

Primary: Contrast Mechanisms - Spectroscopy

Secondary: Brain Function and fMRI - fMRI & Neuromodulation

562-06-003 · fMRI: Preclinical · Wednesday, 13 May, 4:55 PM–5:50 PM · Digital Posters Row C

Keywords: Functional spectroscopy BOLD-fMRI MR Spectroscopy (MRS) Chemogenetic

Accepted

Nathalie Just ^1,2

¹LIFMET, EPFL, Lausanne, Switzerland

²Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Copenhagen, Denmark

Presenting Author: Nathalie Just

Synopsis

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References

1. Just N. Proton functional magnetic resonance spectroscopy in rodents.NMR Biomed. 2021 May;34(5): e4254. doi: 10.1002/nbm.4254. [doi]

2. Provencher SW. Automatic quantitation of localized in vivo 1H spectra with LCModel. NMR Biomed. 2001 Jun;14(4):260-4. doi: 10.1002/nbm.698. [doi]

3. Simpson R, Devenyi GA, Jezzard P, Hennessy TJ, Near J. Advanced processing and simulation of MRS data using the FID appliance (FID-A)-An open source, MATLAB-based toolkit. Magn Reson Med. 2017 Jan;77(1):23-33. doi: 10.1002/mrm.26091. [doi]

4. Klomp A, Tremoleda JL, Wylezinska M, Nederveen AJ, Feenstra M, Gsell W, Reneman L. Lasting effects of chronic fluoxetine treatment on the late developing rat brain: age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI.Neuroimage. 2012 Jan 2;59(1):218-26. doi: 10.1016/j.neuroimage.2011.07.082. [doi]

5. Schrantee A, Tremoleda JL, Wylezinska-Arridge M, Bouet V, Hesseling P, Meerhoff GF, de Bruin KM, Koeleman J, Freret T, Boulouard M, Desfosses E, Galineau L, Gozzi A, Dauphin F, Gsell W, Booij J, Lucassen PJ, Reneman L. Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate.PLoS One. 2017 Feb 27;12(2):e0172776. doi: 10.1371/journal.pone.0172776. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/562-06-003