Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-04-012 ISMRM Abstract

Iron Dysregulation in Cerebral Small Vessel Disease: A Quantitative Susceptibility Mapping Study Revealing Spatial Patterns a

Primary: Neuro - Blood Vessels
Secondary: Neuro - White Matter
663-04-012 · Cerebral Small Vessel Disease: Network, Glymphatic, and Blood Flow · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row D
Keywords: Cognitive impairment White Matter Hyperintensities Quantitative Susceptibility Mapping (QSM) Cerebral Small Vessel Disease (CSVD)
Accepted
Pengcheng Liang , Meng Li1, Jing Li2, Lingfei Guo3, Changhu Liang3
1Jena University Hospital, Jena, Germany
2Beijing Tsinghua Changgung Hospital, Beijing, China
3Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
Presenting Author: Pengcheng Liang

Synopsis

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References

1. Prins ND, Scheltens P. White matter hyperintensities, cognitive impairment and dementia: an update. Nat Rev Neurol 2015;11:157-65.
2. Adeniyi PA, et al. Ferroptosis of Microglia in Aging Human White Matter Injury. Ann Neurol 2023
3. Ryan SK, et al. Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration. Nat Neurosci 2023;26:12-26.
4. Wang Y, et al. Clinical Quantitative Susceptibility Mapping (QSM) – Biometal Imaging and its Emerging Roles in Patient Care. J Magn Reson Imaging 2017;46:951-71.
5. Staals J, et al. Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden. Neurology 2014;83:1228-34.
6. Liu Z, et al. MEDI+0: Morphology enabled dipole inversion with automatic uniform cerebrospinal fluid zero reference for quantitative susceptibility mapping. Magn Reson Med 2018;79:2795-803.
7. Ayton S, et al. Deferiprone in Alzheimer Disease: A Randomized Clinical Trial. JAMA Neurol 2025;82:11.
8. Ferris JK, et al. In vivo myelin imaging and tissue microstructure in white matter hyperintensities and perilesional white matter. Brain Commun 2022;4:fcac142.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-04-012