Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
570-09-230 ISMRM Abstract

Multiexponential contributions in T1xT2 relaxometry

Primary: Contrast Mechanisms - Relaxometry
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
570-09-230 · Quantitative Imaging · Wednesday, 13 May, 4:00 PM–4:55 PM · Traditional Posters | Exhibition Hall
Keywords: Relaxometry Multidimensional MRI Multi-component Relaxometry
Accepted
Nikos Priovoulos 1, Hongyan Liu1, Dan Benjamini2, Amy Howard1,3, Aaron T Hess1, Karla Miller1
1Oxford Centre for Integrative Neuroimaging (OXCIN), University of Oxford, Oxford, United Kingdom
2National Institute of Health, Bethesda, United States of America
3Department of Bioengineering, Imperial College London, London, United Kingdom
Presenting Author: Nikos Priovoulos

Synopsis

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References

1. Fischer, H. W., Van Haverbeke, Y., Schmitz-Feuerhake, I. & Muller, R. N. The uncommon longitudinal relaxation dispersion of human brain white matter. Magn. Reson. Med. 9, 441–446 (1989).
2. Labadie, C. et al. Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields. Magn. Reson. Med. 71, 375–387 (2014).
3. Armspach, J.-P., Gounot, D., Rumbach, L. & Chambron, J. In vivo determination of multiexponential T2 relaxation in the brain of patients with multiple sclerosis. Magn. Reson. Imaging 9, 107–113 (1991).
4. Song, Y.-Q. et al. T1–T2 Correlation Spectra Obtained Using a Fast Two-Dimensional Laplace Inversion. J. Magn. Reson. 154, 261–268 (2002).
5. Aue, W. P., Bartholdi, E. & Ernst, R. R. Two‐dimensional spectroscopy. Application to nuclear magnetic resonance. J. Chem. Phys. 64, 2229–2246 (1976).
6. Kim, D., Wisnowski, J. L., Nguyen, C. T. & Haldar, J. P. PROBING IN VIVO MICROSTRUCTURE WITH T1-T2 RELAXATION CORRELATION SPECTROSCOPIC IMAGING. Proc. IEEE Int. Symp. Biomed. Imaging 2018, 675–678 (2018).
7. Benjamini, D. & Basser, P. J. Use of marginal distributions constrained optimization (MADCO) for accelerated 2D MRI relaxometry and diffusometry. J. Magn. Reson. 271, 40–45 (2016).
8. Benjamini, D. & Basser, P. J. Magnetic resonance microdynamic imaging reveals distinct tissue microenvironments. NeuroImage 163, 183–196 (2017).

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http://echo.ismrm.org/p/ISMRM2026/570-09-230