Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-04-002 ISMRM Abstract

Region-Specific Default Mode Network Connectivity Alterations in Traumatic Brain Injury: A Resting-State fMRI Analysis

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Neuro - Traumatic Brain Injury
463-04-002 · Advanced Microstructural Imaging of White Matter and Traumatic Brain Injury · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row D
Keywords: Mild Traumatic Brain Injury Default mode network Resting-state functional MRI
Accepted
Siddharth Singh1, Durgesh K Dwivedi 1, S Senthil Kumaran2, BV Rathish Kumar3, Anit Parihar1, Anil Chandra4, Bal K Ojha4, Chhitij Srivastava4, Shailendra M Tripathi5, Sudhir K Pathak6
1Radiodiagnosis, King George's Medical University, Lucknow, India
2Nuclear Magnetic Resonance (NMR), All India Institute of Medical Sciences, New Delhi, India
3Department of Mathematics and Statistics, Indian Institute of Technology, Kanpur, India
4Neurosurgery, King George's Medical University, Lucknow, India
5Department of Geriatric Mental Health, King George's Medical University, Lucknow, India
6Learning Research and Development Center, University of Pittsburgh, Pittsburgh, United States of America
Presenting Author: Durgesh K Dwivedi

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. 1. Ru D, Zhang J, Wei L, Zhang Z, Wang Y, Zhou F, Wu G, Yuan Q, Du Z, Wang E, Hu J. Clinical Insights Into Default Mode Network Abnormalities in Mild Traumatic Brain Injury: Unraveling Axonal Injury Through Functional, Structural, and Molecular Analyses. CNS Neurosci Ther. 2024 Dec;30(12):e70188. doi: 10.1111/cns.70188. PMID: 39722654; PMCID: PMC11669841. [doi] [pmid]
2. Aswendt M, Hoehn M. Functional hyperconnectivity related to brain disease: maladaptive process or element of resilience? Neural Regen Res. 2023 Jul;18(7):1489-1490. doi: 10.4103/1673-5374.361541. PMID: 36571347; PMCID: PMC10075104. [doi] [pmid]
3. Bernier, R. A., Roy, A., Venkatesan, U. M., Grossner, E. C., Brenner, E. K., & Hillary, F. G. (2017). Dedifferentiation Does Not Account for Hyperconnectivity after Traumatic Brain Injury. Frontiers in Neurology, 8, 260867. https://doi.org/10.3389/fneur.2017.00297 [doi]
4. Zhou, Yongxia, Michael P. Milham, Yvonne W. Lui, Laura Miles, Joseph Reaume, Daniel K. Sodickson, Robert I. Grossman, and Yulin Ge. "Default-mode network disruption in mild traumatic brain injury." Radiology 265, no. 3 (2012): 882-892. DOI: https://doi.org/10.1148/radiol.12120748 [doi]
5. Bonnelle, Valerie, Robert Leech, Kirsi M. Kinnunen, Tim E. Ham, Cristian F. Beckmann, Xavier De Boissezon, Richard J. Greenwood, and David J. Sharp. "Default mode network connectivity predicts sustained attention deficits after traumatic brain injury." Journal of Neuroscience 31, no. 38 (2011): 13442-13451.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/463-04-002