Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
452-02-001 / 452-02-001 ISMRM Abstract

Multi-echo EPI improves image quality and functional connectivity mapping in resting-state fMRI on a 1.5T MR-Linac

Primary: Interventional - MR-Guided Radiotherapy
Secondary: Neuro - Tumors
452-02-001 · Methodology: Acquisition and Analysis · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
452-02-001 · Methodology: Acquisition and Analysis · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
Keywords: MR-Guided Radiotherapy Brain function Glioblastoma Resting-state fMRI
Accepted
Eaman Almasri 1,2, Liam Lawrence1,2, James Stewart3, Mark Ruschin3, Aimee Theriault3, Jay Detsky3, Chia-Lin Tseng3, Hany Soliman3, Arjun Sahgal3, Angus Lau1,2,4,5
1Physical Science Platform, Sunnybrook Research Institute, Toronto, Canada
2Department of Medical Biophysics, University of Toronto, Toronto, Canada
3Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada
4Department of Radiation Oncology, University of Toronto, Toronto, Canada
5Medical Physics, Odette Cancer Centre, Toronto, Canada
Presenting Author: Eaman Almasri

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Wen, Patrick Y., and Santosh Kesari. "Malignant gliomas in adults." New England Journal of Medicine 359.5 (2008): 492-507. DOI: 10.1056/NEJMra0708126 [doi]
2. Biswal, Bharat B. "Resting state fMRI: a personal history." Neuroimage 62.2 (2012): 938-944. DOI: 10.1016/j.neuroimage.2012.01.090 [doi]
3. Stoecklein, Veit M., et al. "Resting-state fMRI detects alterations in whole brain connectivity related to tumor biology in glioma patients." Neuro-oncology 22.9 (2020): 1388-1398. DOI: 10.1093/neuonc/noaa044 [doi]
4. Rhodes, Chandler Sours, et al. "The feasibility of integrating resting-state fMRI networks into radiotherapy treatment planning." Journal of Medical Imaging and Radiation Sciences 50.1 (2019): 119-128. DOI: 10.1016/j.jmir.2018.09.003 [doi]
5. Raaymakers, Bas W., et al. "Integrating a 1.5 T MRI scanner with a 6 MV accelerator: proof of concept." Physics in Medicine & Biology 54.12 (2009): N229. DOI: 10.1088/0031-9155/54/12/N01 [doi]
6. Lagendijk, Jan JW, et al. "MRI/linac integration." Radiotherapy and Oncology 86.1 (2008): 25-29. DOI: 10.1016/j.radonc.2007.10.034 [doi]
7. Detsky, J. "NCT04726397-UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: A Phase 2 Trial (UNITED)." ClinicalTrials. gov 3 (2021).
8. Almasri, Eaman, et al. “First demonstration of resting-state functional MRI on a 1.5T MR-Linac to assess functional connectivity in glioblastoma patients.” International Society for Magnetic Resonance in Medicine (ISMRM) 2025 Annual Meeting, Honolulu, Hawaii, Abstract 0887, 2025.
9. de Mol van Otterloo, Sophie R., et al. "The MOMENTUM study: an international registry for the evidence-based introduction of MR-guided adaptive therapy." Frontiers in oncology 10 (2020): 1328. DOI: 10.3389/fonc.2020.01328 [doi]
10. Hoogcarspel, Stan J., et al. "Characterization of the first RF coil dedicated to 1.5 T MR guided radiotherapy." Physics in Medicine & Biology 63.2 (2018): 025014. DOI: 10.1088/1361-6560/aaa303 [doi]
11. Jenkinson, Mark, et al. "Fsl." Neuroimage 62.2 (2012): 782-790. DOI: 10.1016/j.neuroimage.2011.09.015 [doi]
12. DuPre, Elizabeth, et al. "TE-dependent analysis of multi-echo fMRI with* tedana." Journal of Open Source Software 6.66 (2021): 3669. DOI: 10.21105/joss.03669 [doi]
13. Whitfield-Gabrieli, Susan, and Alfonso Nieto-Castanon. "Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks." Brain connectivity 2.3 (2012): 125-141. DOI: 10.1089/brain.2012.0073 [doi]
14. Gilmore, Adrian W., et al. "A comparison of single-and multi-echo processing of functional MRI data during overt autobiographical recall." Frontiers in Neuroscience 16 (2022): 854387. https://doi.org/10.3389/fnins.2022.854387 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/452-02-001