Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
403-01-010 ISMRM Abstract

Detection of white matter degeneration of the visual pathway via diffusion-weighted MRI

Primary: Diffusion - Diffusion Analysis & Visualization
Secondary: Neuro - White Matter
403-01-010 · Diffusion Tractography · Tuesday, 12 May, 8:20 AM–10:10 AM · Auditorium 1
Keywords: White Matter Diffusion Tensor Imaging Diffusion-weighted MRI Glaucoma Multi-tensor
Accepted
Daniela Coutiño 1, Judith Guerrero1, César A Domínguez-Frausto1, Marlene Garcia-Guillén1, Ricardo Coronado-Leija2,3,4, Erick Hernández-Gutiérrez5, Maxime Descoteaux6,7,8,9, Martin Ayala10, Mariana Badillo10, Luis Concha1
1Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Queretaro, Mexico
2New York University Grossman School of Medicine, New York, United States of America
3Department of Radiology, New York University Grossman School of Medicine, New York, United States of America
4Department of Radiology, Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America
5Sherbrooke Connectivity Imaging Lab (SCIL), Université de Sherbrooke, Sherbrooke, Canada
6Université de Sherbrooke, Sherbrooke, Canada
7Physics, Université de Sherbrooke, Sherbrooke, Canada
8Department of Computer Science, Université de Sherbrooke, Sherbrooke, Canada
9Computer Science, Université de Sherbrooke, Sherbrooke, Canada
10Servicio de Glaucoma, Instituto Mexicano de Oftalmologia, Mexico
Presenting Author: Daniela Coutiño

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References

1. Basser, P. J., Mattiello, J. & LeBihan, D. MR diffusion tensor spectroscopy and imaging. Biophys. J. 66, 259–267 (1994). DOI: 10.1016/S0006-3495(94)80775-1 [doi]
2. Coronado-Leija, R., Ramirez-Manzanares, A. & Marroquin, J. L. Estimation of individual axon bundle properties by a Multi-Resolution Discrete-Search method. Med. Image Anal. 42, 26–43 (2017). DOI: 10.1016/j.media.2017.06.008 [doi]
3. Tournier, J.-D., Calamante, F. & Connelly, A. Robust determination of the fibre orientation distribution in diffusion MRI: Non-negativity constrained super-resolved spherical deconvolution. NeuroImage 35, 1459–1472 (2007). DOI: 10.1016/j.neuroimage.2007.02.016 [doi]
4. Rojas-Vite, G. et al. Histological validation of per-bundle water diffusion metrics within a region of fiber crossing following axonal degeneration. NeuroImage 201, 116013 (2019). DOI: 10.1016/j.neuroimage.2019.116013 [doi]
5. Raffelt, D. A. et al. Investigating white matter fibre density and morphology using fixel-based analysis. NeuroImage 144, 58–73 (2017). DOI: 10.1016/j.neuroimage.2016.09.029 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/403-01-010