Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-02-013 ISMRM Abstract

Cognitive Decline in Parkinson's Disease: Correlation with Choroid Plexus Volume

Accepted
Meltem Karatas1, Sevim Cengiz2, Dilek Betül Arslan3, Ani Kicik4, Emel Erdogdu5, Basar Bilgic6, Hasmet A Hanagasi7, Tamer Demiralp8,9, Hakan Gurvit7, Esin Ozturk Isik 1,10
1Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey
2College of Technological Innovation, Zayed University, United Arab Emirates
3Biomedical Engineering Department, Istanbul Atlas University, Istanbul, Turkey
4Department of Physiology, Faculty of Medicine, Demircioglu Bilim University, Istanbul, Turkey
5Department of Psychology, Faculty of Arts and Sciences, Isik University, Istanbul, Turkey
6Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Faculty of Medicine, Istanbul University, Istanbul, Turkey
7Behavioral Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
8Neuroimaging Unit Hulusi Behcet Life Sciences Research Center, Istanbul University, Istanbul, Turkey
9Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
10Brain Tumor Research Group, Acibadem University, Istanbul, Turkey
Presenting Author: Esin Ozturk Isik

Synopsis

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References

1. Levit E, Ren Z, Gonzenbach V, Azevedo CJ, Calabresi PA, Cree BA, Freeman L, Longbrake EE, Oh J, Schindler MK, Sicotte NL, Reich DS, Ontaneda D, Sati P, Cao Q, Shinohara RT, Solomon AJ. Choroid plexus volume differentiates MS from its mimics. Mult Scler. 2024 Jul;30(8):1072-1076. doi: 10.1177/13524585241238094. Epub 2024 Mar 13. PMID: 38481081; PMCID: PMC11288781. [doi] [pmid]
2. Jankowska A, Chwojnicki K, Grzywińska M, Trzonkowski P, Szurowska E. Choroid Plexus Volume Change-A Candidate for a New Radiological Marker of MS Progression. Diagnostics (Basel). 2023 Aug 14;13(16):2668. doi: 10.3390/diagnostics13162668. PMID: 37627928; PMCID: PMC10453931. [doi] [pmid]
3. Hochstetler A, Lehtinen MK. Choroid Plexus as a Mediator of CNS Inflammation in Multiple Sclerosis. Mult Scler. 2024 Dec;30(5_suppl):19-23. doi: 10.1177/13524585241292974. Epub 2024 Nov 6. PMID: 39503321; PMCID: PMC11634642 [doi] [pmid]
4. Čarna M, Onyango IG, Katina S, Holub D, Novotny JS, Nezvedova M, Jha D, Nedelska Z, Lacovich V, Vyvere TV, Houbrechts R, Garcia-Mansfield K, Sharma R, David-Dirgo V, Vyhnalek M, Texlova K, Chaves H, Bakkar N, Pertierra L, Vinkler M, Markova H, Laczo J, Sheardova K, Hortova-Kohoutkova M, Frič J, Forte G, Kaňovsky P, Belaškova S, Damborsky J, Hort J, Seyfried NT, Bowser R, Sevlever G, Rissman RA, Smith RA, Hajduch M, Pirrotte P, Spacil Z, Dammer EB, Limbäck-Stokin C, Stokin GB. Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimers Dement. 2023 Aug;19(8):3537-3554. doi: 10.1002/alz.12970. Epub 2023 Feb 24. PMID: 36825691; PMCID: PMC10634590. [doi] [pmid]
5. Choi JD, Moon Y, Kim HJ, Yim Y, Lee S, Moon WJ. Choroid Plexus Volume and Permeability at Brain MRI within the Alzheimer Disease Clinical Spectrum. Radiology. 2022 Sep;304(3):635-645. doi: 10.1148/radiol.212400. Epub 2022 May 17. PMID: 35579521. [doi] [pmid]
6. Jiang J, Zhuo Z, Wang A, Li W, Jiang S, Duan Y, Ren Q, Zhao M, Wang L, Yang S, Awan MUN, Liu Y, Xu J. Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer's continuum. Alzheimers Res Ther. 2024 Jul 3;16(1):149. doi: 10.1186/s13195-024-01520-w. PMID: 38961406; PMCID: PMC11221040. [doi] [pmid]
7. Jeong SH, Park CJ, Jeong HJ, Sunwoo MK, Ahn SS, Lee SK, Lee PH, Kim YJ, Sohn YH, Chung SJ. Association of choroid plexus volume with motor symptoms and dopaminergic degeneration in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2023 Dec;94(12):1047-1055. doi: 10.1136/jnnp-2023-331170. Epub 2023 Jun 30. PMID: 37399288. [doi] [pmid]
8. Jeong SH, Jeong HJ, Sunwoo MK, Ahn SS, Lee SK, Lee PH, Kim YJ, Sohn YH, Park CJ, Chung SJ. Association between choroid plexus volume and cognition in Parkinson disease. Eur J Neurol. 2023 Oct;30(10):3114-3123. doi: 10.1111/ene.15999. Epub 2023 Aug 6. PMID: 37498202. [doi] [pmid]
9. Yin X, Wang M, Zhao F, Li F, Tang Y, Wang X, Duan C, Wang S, Xiong Y, Yao J, Chen T, Wang Z, Li Y, Lou X, Gao Z. Choroid plexus area and choroid plexus /lateral ventricle area index are potential imaging markers for freezing of gait in Parkinson's disease. Neurobiol Dis. 2025 Aug;212:106984. doi: 10.1016/j.nbd.2025.106984. Epub 2025 Jun 2. PMID: 40467010. [doi] [pmid]
10. Fedorov A, Beichel R, Kalpathy-Cramer J, Finet J, Fillion-Robin JC, Pujol S, Bauer C, Jennings D, Fennessy F, Sonka M, Buatti J, Aylward S, Miller JV, Pieper S, Kikinis R. 3D Slicer as an image computing platform for the Quantitative Imaging Network. Magn Reson Imaging. 2012 Nov;30(9):1323-41. doi: 10.1016/j.mri.2012.05.001. Epub 2012 Jul 6. PMID: 22770690; PMCID: PMC3466397. [pmid] [doi] [pmid]
11. Bannai D, Cao Y, Keshavan M, Reuter M, Lizano P. Manual Segmentation of the Human Choroid Plexus Using Brain MRI. J Vis Exp. 2023 Dec 15;(202). doi:10.3791/65341. PMID: 38163279. [pmid] [doi] [pmid]
12. Manjón JV, Romero JE, Vivo-Hernando R, Rubio G, Aparici F, de la Iglesia-Vaya M, Coupé P. vol2Brain: A New Online Pipeline for Whole Brain MRI Analysis. Front Neuroinform. 2022 May 24;16:862805. doi: 10.3389/fninf.2022.862805. PMID: 35685943; PMCID: PMC9171328. [pmid] [doi] [pmid]

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