Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
305-04-009 / 271-01-012 ISMRM Abstract

Accuracy and Sensitivity of 3D qDESS in T2-mapping of Skeletal Muscle Before and After Exercise-induced Increases in T2

Accepted
Gabriel Rossetto 1, Rory Brown1,2, Matthew Birkbeck1,2, David M Higgins3, Kieren G Hollingsworth1
1Newcastle Magnetic Resonance Centre, Translational and Clinical Research Institue, Newcastle University, Newcastle upon Tyne, United Kingdom
2Northern Medical Physics and Clinical Engineering, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
3Clinical Science, Philips, United Kingdom
Presenting Author: Gabriel Rossetto

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Dwyer, A. J. et al. Short-Ti inversion-recovery pulse sequence: analysis and initial experience in cancer imaging. Radiology 168, 827–836. issn: 00338419 (3 Sept. 1988).
2. Dixon, W. T. Simple proton spectroscopic imaging. Radiology 153, 189–194. issn: 00338419 (1 Oct. 1984).
3. Glover, G. H. & Schneider, E. Three-point dixon technique for true water/fat decomposition with B0 inhomogeneity correction. Magnetic Resonance in Medicine 18, 371–383. issn: 1522-2594 (2 Apr. 1991).
4. Degardin, A. et al. Morphologic imaging in muscular dystrophies and inflammatory myopathies. Skeletal Radiology 39, 1219–1227. issn: 03642348 (12 May 2010).
5. Friedman, S. D. et al. Longitudinal features of stir bright signal in FSHD1. Muscle Nerve 49, 257–260. issn: 1097-4598 (2 Feb. 2014).
6. Ferguson, M. R. et al. MRI change metrics of facioscapulohumeral muscular dystrophy: Stir and T1. Muscle Nerve 57, 905–912. issn: 1097-4598 (6 June 2018).
7. Dahlqvist, J. R. et al. Evaluation of inflammatory lesions over 2 years in facioscapulohumeral muscular dystrophy. Neurology 95, E1211–E1221. issn: 1526632X (9 Sept. 2020).
8. Tawil, R., Shaw, D. W., van der Maarel, S. M. & Tapscott, S. J. Clinical trial preparedness in facioscapu- lohumeral dystrophy: Outcome measures and patient access: 8–9 April 2013, Leiden, The Netherlands. Neuromuscular Disorders 24, 79–85. issn: 0960-8966 (1 Jan. 2014).
9. Azzabou, N., Sousa, P. L. D., Caldas, E. & Carlier, P. G. Validation of a Generic Approach to Muscle Water T2 Determination at 3T in Fat-Infiltrated Skeletal Muscle. Original Research J. Magn. Reson. Imaging 41, 645–653 (2015).
10. Mankodi, A. et al. Skeletal muscle water T2 as a biomarker of disease status and exercise effects in patients with Duchenne muscular dystrophy. Neuromuscular Disorders 27, 705–714. issn: 0960-8966 (8 Aug. 2017).
11. Hennig, J. Multiecho imaging sequences with low refocusing flip angles. Journal of Magnetic Resonance (1969) 78, 397–407. issn: 0022-2364 (3 July 1988).
12. Marty, B. et al. Simultaneous muscle water T2 and fat fraction mapping using transverse relaxometry with stimulated echo compensation. NMR in Biomedicine 29, 431–443. issn: 1099-1492 (4 Apr. 2016).
13. Chaudhari, A. S. et al. Five-minute knee MRI for simultaneous morphometry and T 2 relaxometry of cartilage and meniscus and for semiquantitative radiological assessment using double-echo in steady-state at 3T. Journal of Magnetic Resonance Imaging 47, 1328–1341. issn: 15222586 (5 May 2018).
14. Saab, G., Thompson, R. T. & Marsh, G. D. Effects of exercise on muscle transverse relaxation determined by MR imaging and in vivo relaxometry. https://doi.org/10.1152/jappl.2000.88.1.226 88, 226–233. issn: 87507587 (1 2000). [doi]
15. Dooley, K. et al. Spatial muscle activation patterns during different leg exercise protocols in physically ac- tive adults using muscle functional MRI: a systematic review. https://doi.org/10.1152/japplphysiol.00290.2020 129, 934–946. issn: 15221601 (4 Oct. 2020). [doi]
16. Holodov, M. et al. Probing muscle recovery following downhill running using precise mapping of MRI T2 relaxation times. Magnetic Resonance in Medicine 90, 1990–2000. issn: 15222594 (5 Nov. 2023).
17. Barzaghi, L. et al. Muscle diffusion tensor imaging in facioscapulohumeral muscular dystrophy. Muscle Nerve 70, 248–256. issn: 1097-4598 (2 Aug. 2024).

Cite this abstract