Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-06-007 ISMRM Abstract

Impact of childhood adversity on age-related changes of brain metabolites and tissue parameters using 1H MRS and MPM at 3T

Primary: Neuro - Aging
Secondary: Contrast Mechanisms - Spectroscopy
362-06-007 · Neuroimaging Biomarkers of Aging, Vascular Health, and Dementia · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row C
Keywords: Aging Neuroinflammation Multi-Parameter-Mapping 3 T magnetic resonance spectroscopy Early-life stress (ELS)
Accepted
Ralf Mekle 1, Martin Bauer2,3, Lara Fleck2, Alma Kathmann2, Dinesh K Deelchand4,5, Claudia Buss2,6,7,8, Sonja Entringer2,6,7,8, Jochen B Fiebach1, Matthias Endres1,7,9,10, Christine Heim2,7,10
1Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Stroke Research Berlin, Berlin, Germany
2Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Psychology, Berlin, Germany
3Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, Germany
4University of Minnesota, CMRR, United States of America
5Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, United States of America
6Development, Health, and Disease Research Program, University of California, Irvine, Orange, United States of America
7German Center for Mental Health, Berlin, Germany
8German Center for Child and Adolescent Health, Berlin, Germany
9Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neurology with Experimental Neurology, Berlin, Germany
10Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt- Universität zu Berlin, Neurocure Cluster of Excellence, Berlin, Germany
Presenting Author: Ralf Mekle

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References

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http://echo.ismrm.org/p/ISMRM2026/362-06-007