Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-01-001 ISMRM Abstract

Time-dependent Low b-value Diffusion Tensor Imaging for Mapping Advection- and Diffusion-Resolved CSF Dynamics

Primary: Neuro - Neurofluids
Secondary: Diffusion - Diffusion Acquisition
363-01-001 · Neurological Application of Advanced Diffusion and Quantitative MRI · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row D
Keywords: Neurofluids Velocity & Flow Diffusion Tensor Imaging Time-dependent diffusion MRI Cerebrospinal fluid flow
Accepted
Yoshitaka Bito 1,2, Hiroyuki Kameda2,3,4, Kinya Ishizaka5, Noriyuki Fujima1,2,4, Yukie Shimizu1,2,4, Naoya Kinota1,2,4, Daisuke Kato1,4, Takaaki Fujii1,4, Kenji Hirata1,2,6, Kohsuke Kudo1,2,4
1Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, Sappro, Japan
2Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sappro, Japan
3Department of Radiology, Faculty of Dental Medicine, Hokkaido University, Sappro, Japan
4Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sappro, Japan
5Department of Radiological Technology, Hokkaido University Hospital, Sappro, Japan
6Department of Nuclear Medicine, Hokkaido University Hospital, Sappro, Japan
Presenting Author: Yoshitaka Bito

Synopsis

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References

1. Harrison IF, Siow B, Akilo AB, Evans PG, Ismail O, Ohene Y, Nahavandi P, Thomas DL, Lythgoe MF, Wells JA. Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI. Elife 2018;7:e34028. https://doi.org/10.7554/elife.34028. [doi]
2. Bito Y, Harada K, Ochi H, Kudo K. Low b-value diffusion tensor imaging for measuring pseudorandom flow of cerebrospinal fluid. Magn Reson Med 2021;86(3):1369-1382. https://doi.org/10.1002/mrm.28806. [doi]
3. Wright AM, Wu Y-C, Feng L, Wen Q. Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements. NMR in Biomedicine 2024;e5162. https://doi.org/10.1002/nbm.5162. [doi]
4. Bito Y, Ochi H, Shirase R, Yokohama W, Harada K, Kudo K. Low b-value diffusion tensor imaging to analyze the dynamics of cerebrospinal fluid: resolving intravoxel pseudorandom motion into ordered and disordered motions. Magn Reson Med Sci 2025;24(1):46-57. https://doi.org/10.2463/mrms.mp.2023-0081. [doi]
5. Otani T, Bito Y, Yamada S, Watanabe Y, Wada S. A theoretical interpretation of diffusion weighted and intravoxel incoherent motion imaging for cerebrospinal fluid flow. Magn Reson Med. 2025 Sep 4. https://doi.org/10.1002/mrm.70062. [doi]
6. Bito Y, Kameda H, Fujima N, Kinota N, Kato D, Fujii T, Ochi H, Ishizaka K, Hirata K, Kudo K. Formulation and simulation of low b-value DTI of pseudorandom flow in CSF. ISMRM 2025;#451.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-01-001