561-03-004 ISMRM Abstract

Accelerated MTE-NODDI Acquisition By Single-Shot Multi-echo EPI for Clinically Feasible TE-Independent Microstructure Imaging

Primary: Acquisition & Reconstruction - Pulse Sequence Design: Neuro

Secondary: Diffusion - Microstructure

561-03-004 · Fancy Sequences and Encoding Strategies · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row B

Keywords: Diffusion Acquisition Multi-echo EPI Neurite orientation dispersion and density imaging Diffusion-relaxation Multi-compartment diffusion MRI

Accepted

Liam Timms ^1,2, Miriam Hewlett^1,2, Cemre Ariyurek^1,2, Sila Kurugol^1,2, Onur Afacan^1,2

¹Radiology, Boston Children's Hospital, Boston, United States of America

²Harvard Medical School, Boston, United States of America

Presenting Author: Liam Timms

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References

1. Zhang H, Schneider T, Wheeler-Kingshott CA, Alexander DC. NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage. 2012 Jul 16;61(4):1000-16. doi: 10.1016/j.neuroimage.2012.03.072. Epub 2012 Mar 30. PMID: 22484410. [doi] [pmid]

2. Gong T, Tong Q, He H, Sun Y, Zhong J, Zhang H. MTE-NODDI: Multi-TE NODDI for disentangling non-T2-weighted signal fractions from compartment-specific T2 relaxation times. Neuroimage. 2020 Aug 15;217:116906. doi: 10.1016/j.neuroimage.2020.116906. Epub 2020 May 7. PMID: 32387626. [doi] [pmid]

3. Karamched SR, Gorup D, Tolomeo D, Brooks LJ, Gong T, Jørgensen ACS, Hill CS, Clements M, Kalber TL, Wells JA, Stuckey DJ, Thorne L, Shahrezaei V, Marguerat S, Zhang H, Parrinello S, Lythgoe MF. Detecting glioblastoma infiltration beyond conventional imaging tumour margins using MTE-NODDI. Imaging Neurosci (Camb). 2025 Feb 18;3:imag_a_00472. doi: 10.1162/imag_a_00472. PMID: 40800943; PMCID: PMC12319949. [doi] [pmid]

4. Timms, Liam, Mustafa Utkur, Cemre Ariyurek, Sila Kurugol, and Onur Afacan. “Fast T2-IVIM Imaging with Distortion & Motion Correction for Quantitative Mapping in the Abdomen.” Paper presented at 2025 ISMRM & ISMRT Annual Meeting, Honolulu, HI, USA. ISMRM Annual Meeting, ISMRM, 2025.

5. Daducci A, Canales-Rodríguez EJ, Zhang H, Dyrby TB, Alexander DC, Thiran JP. Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data. Neuroimage. 2015 Jan 15;105:32-44. doi: 10.1016/j.neuroimage.2014.10.026. Epub 2014 Oct 22. PMID: 25462697. [doi] [pmid]

6. Utkur M, Timms L, Kurugol S, Afacan O. Ultrafast and robust T2 mapping using optimized single-shot multi-echo planar imaging with alternating blips. Magn Reson Med. 2025 Aug;94(2):530-540. doi: 10.1002/mrm.30516. Epub 2025 Apr 28. PMID: 40294097; PMCID: PMC12140905. [doi] [pmid]

7. Casey BJ, Cannonier T, Conley MI, Cohen AO, Barch DM, Heitzeg MM, Soules ME, Teslovich T, Dellarco DV, Garavan H, Orr CA, Wager TD, Banich MT, Speer NK, Sutherland MT, Riedel MC, Dick AS, Bjork JM, Thomas KM, Chaarani B, Mejia MH, Hagler DJ Jr, Daniela Cornejo M, Sicat CS, Harms MP, Dosenbach NUF, Rosenberg M, Earl E, Bartsch H, Watts R, Polimeni JR, Kuperman JM, Fair DA, Dale AM; ABCD Imaging Acquisition Workgroup. The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites. Dev Cogn Neurosci. 2018 Aug;32:43-54. doi: 10.1016/j.dcn.2018.03.001. Epub 2018 Mar 14. PMID: 29567376; PMCID: PMC5999559. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/561-03-004