Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-05-005 ISMRM Abstract

Feasibility of In Vivo 3D Whole-Brain Transient Motion Imaging

Primary: Contrast Mechanisms - Elastography
Secondary: Neuro - Traumatic Brain Injury
461-05-005 · Advances in Neuroimaging and Biomarkers for Brain Health and Disease · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row B
Keywords: MRE Pulse sequence developoment Repetitive mild traumatic brain injury Transient brain motion Brain biomechanics
Accepted
Xiang Shan1, Yi Sui1, Yuan Le1, Emi Hojo1, Daiki Ito 1, David B Soma2, Daniel J Christoffer3, Armando Manduca4, Richard Ehman1, John III Huston1, Ziying Yin1
1Department of Radiology, Mayo Clinic, Rochester, United States of America
2Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, United States of America
3Department of Sports Medicine, Mayo Clinic, Rochester, United States of America
4Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, United States of America
Presenting Author: Daiki Ito

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References

1. Shan X, Murphy MC, Sui Y, et al. Magnetic Resonance Elastography-Based Technique to Assess the Biomechanics of the Skull-Brain Interface: Repeatability and Age-Sex Characteristics. Journal of Neurotrauma 2023;40(19-20):2193-2204
2. Shan X, Murphy MC, Sui Y, et al. MR elastography-based detection of impaired skull-brain mechanical decoupling performance in response to repetitive head impacts. European Radiology 2025;35(6):3613-3624, doi:10.1007/s00330-024-11265-7 [doi]
3. Escarcega JD, Okamoto RJ, Alshareef AA, et al. Effects of anatomy and head motion on spatial patterns of deformation in the human brain. Annals of Biomedical Engineering 2025;53(4):867-880, doi:10.1007/s10439-024-03671-1 [doi]
4. McCracken PJ, Manduca A, Felmlee J, et al. Mechanical transient-based magnetic resonance elastography. Magnetic Resonance in Medicine 2005;53(3):628-639, doi:https://doi.org/10.1002/mrm.20388 [doi]
5. Le Y, Chen J, Rossman PJ, et al. Wavelet MRE: Imaging propagating broadband acoustic waves with wavelet-based motion-encoding gradients. Magnetic Resonance in Medicine 2024;91(5):1923-1935, doi:https://doi.org/10.1002/mrm.29972 [doi]
6. Le Y, Shan X, Glaser KJ, et al. Detection of transient tissue displacement using wavelet MR elastography: Phantom validation and in vivo human brain repeatability study. Magnetic Resonance in Medicine 2025;94(5):1997-2009, doi:https://doi.org/10.1002/mrm.30612 [doi]
7. Sui Y, Arani A, Trzasko JD, et al. TURBINE-MRE: A 3D hybrid radial-Cartesian EPI acquisition for MR elastography. Magnetic Resonance in Medicine 2021;85(2):945-952, doi:https://doi.org/10.1002/mrm.28445 [doi]
8. Kleiven S. Predictors for traumatic brain injuries evaluated through accident reconstructions. SAE Technical Paper: 2007.
9. Sullivan S, Eucker SA, Gabrieli D, et al. White matter tract-oriented deformation predicts traumatic axonal brain injury and reveals rotational direction-specific vulnerabilities. Biomechanics and Modeling in Mechanobiology 2015;14(4):877-896, doi:10.1007/s10237-014-0643-z [doi]

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http://echo.ismrm.org/p/ISMRM2026/461-05-005