Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
370-04-036 ISMRM Abstract

Quantitative Analysis of Substantia Nigra Margin Blurring for Early Parkinson’s Disease Diagnosis

Primary: Neuro - Parkinson's Disease
Secondary: Neuro - Other Neurodegeneration
370-04-036 · Analysis in Neurodegenerative Disease · Monday, 11 May, 1:50 PM–2:45 PM · Traditional Posters | Exhibition Hall
Keywords: Substantia Nigra Boundary smoothing Parkinsons Disease
Accepted
fei liu, guangbin wang1, Xiuzheng Yue2,3, Tao Gong 4
1Department of Radiograpy, Shandong Provincial Hospital Affiliated to Shandong First Medical University (Shandong Provincial Hospital), Jinan, China
2Medical Imaging Center, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China
3Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
4Departments of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250022, China
Presenting Author: Tao Gong

Synopsis

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References

1. Bae YJ et al. Imaging the Substantia Nigra in Parkinson Disease and Other Parkinsonian Syndromes. Radiology. 2021; 301(2):260-274
2. Pyatigorskaya N et al. Comparative Study of MRI Biomarkers in the Substantia Nigra to Discriminate Idiopathic Parkinson Disease. AJNR Am J Neuroradiol. 2018; 39(8):1460-1467
3. Blazejewska AI et al. Visualization of Nigrosome 1 and Its Loss in Parkinson’s Disease. Neurology. 2013; 81(6):534-540
4. Chen X et al. Imaging of Neuromelanin in Parkinson’s Disease by Using a Fast 3D Gradient Echo Sequence with Magnetization Transfer Contrast. NeuroImage. 2014; 95:224-229
5. Lakhani DA et al. Diagnostic Utility of 7 T Neuromelanin Imaging of the Substantia Nigra in Parkinson’s Disease. NPJ Parkinson’s Dis. 2024; 10:31

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/370-04-036