Synopsis
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404-03-004
ISMRM Abstract
High-Resolution QSM for Choroid Plexus Calcification: A Biomarker for Chronic Inflammation in Multiple Sclerosis
Accepted
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1. Sun Z, Li C, Muccio M, et al. Vascular Aging in the Choroid Plexus: A 7T Ultrasmall Superparamagnetic Iron Oxide (USPIO)-MRI Study. J Magn Reson Imaging. 2024;60(6):2564-2575. doi:10.1002/jmri.29381 [doi]
2. Talhada D C-BA, Duarte AC, Costa AR, Quintela T, Tomás J, Gonçalves I, Santos CRA. The choroid plexus: Simple structure, complex functions. Journal of Neuroscience Research. 2019;98(5):751-753. doi:https://doi.org/10.1002/jnr.24571 [doi]
3. Javed KR, Vamsi; Lui, Forshing. Neuroanatomy, Choroid Plexus. StatPearls [Internet]: StatsPearls Publishing; 2023.
4. Mortazavi MM, Griessenauer CJ, Adeeb N, et al. The choroid plexus: a comprehensive review of its history, anatomy, function, histology, embryology, and surgical considerations. Childs Nerv Syst. 2014;30(2):205-214. doi:10.1007/s00381-013-2326-y [doi]
5. Hubert V, Chauveau F, Dumot C, et al. Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review. Front Mol Neurosci. 2019;12:34. doi: 10.3389/fnmol.2019.00034 [doi]
6. Dixon GA, Perez CA. Multiple Sclerosis and the Choroid Plexus: Emerging Concepts of Disease Immunopathophysiology. Pediatr Neurol. 2020;103:65-75. doi: 10.1016/j.pediatrneurol.2019.08.007 [doi]
7. Grasso EA, Bloy L, Kaplan P, et al. Choroid Plexus Volume in Pediatric-Onset Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm. 2024;11(6):e200319. doi: 10.1212/NXI.0000000000200319 [doi]
8. Butler T, Wang XH, Chiang GC, et al. Choroid plexus calcification correlates with cortical microglial activation in humans: a multimodal PET, CT, MRI study. American Journal of Neuroradiology. 2023;44(7):776-782. doi: 10.3174/ajnr.A7903 [doi]
9. Truong V, Sawan H, Wright S, Chen Y. SUPREME: Susceptibility with Ultra-high-resolution Parallel REconstruction of Multi-Echo. Paper presented at: Proc. Intl. Soc. Mag. Reson. Med. (ISMRM25); May 10, 2025, 2025; Honolulu, HI.
10. Penny WD, Friston KJ, Ashburner JT, Kiebel SJ, Nichols TE. Statistical parametric mapping: the analysis of functional brain images. Elsevier; 2011. doi: 10.1016/B978-0-12-372560-8.X5000-1 [doi]
11. Shin H-G, Lee J, Yun YH, et al. χ-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain. Neuroimage. 2021;240:118371. doi: 10.1016/j.neuroimage.2021.118371 [doi]
12. Dimov AV, Gillen KM, Nguyen TD, et al. Magnetic susceptibility source separation solely from gradient echo data: histological validation. Tomography. 2022;8(3):1544-1551. doi: https://doi.org/10.3390/tomography8030127 [doi]
13. Kim M, Ji S, Kim J, et al. χ‐sepnet: deep neural network for magnetic susceptibility source separation. Human Brain Mapping. 2025;46(2):e70136. doi: https://doi.org/10.1002/hbm.70136 [doi]
14. Chen Y, Liu S, Wang Y, Kang Y, Haacke EM. STrategically Acquired Gradient Echo (STAGE) imaging, part I: Creating enhanced T1 contrast and standardized susceptibility weighted imaging and quantitative susceptibility mapping. Magnetic resonance imaging. 2018;46:130-139. doi: 10.1016/j.mri.2017.10.005 [doi]
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http://echo.ismrm.org/p/ISMRM2026/404-03-004