Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-03-006 ISMRM Abstract

Aerobic Fitness Augments Myelin in Men, But Not Women

Primary: Neuro - White Matter
Secondary: Analysis Methods - Data Processing
566-03-006 · Radiomics Potpourri · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row G
Keywords: White Matter Myelin Myelin water fraction Sex differences Aerobic Fitness
Accepted
Alma Davidson1, Ariana G Olivares2, Adriana Dipple2, Kellie Hoehing3, Alexander Chui3, Vincenzo Lauriola4, Rochelle Goldsmith3, Richard B Lipton5,6, Kenny Ye5, Roman Fleysher 2,7,8, Michael Lipton1,2
1Department of Biomedical Engineering, Columbia University, New York, United States of America
2Department of Radiology, Columbia University Irving Medical Center, New York, United States of America
3Department of Medicine, Columbia University Irving Medical Center, New York, United States of America
4Department of Psychiatry, Columbia University Irving Medical Center, New York, United States of America
5Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, United States of America
6Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, United States of America
7Gruss Magnetic Resonance Research Center, Department of Radiology, Albert Einstein College of Medicine, Bronx, United States of America
8Department of Radiology, Gruss Magnetic Resonance Research Center, Albert Einstein College of Medicine, Bronx, United States of America
Presenting Author: Roman Fleysher

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References

1. Tarumi, T. et al. Microstructural organization of the corpus callosum in young endurance athletes: A global tractography study. Frontiers in Neuroscience 16, (2022). doi: 10.3389/fnins.2022.1042426 [doi]
2. van der Weijden, C. W. J. et al. Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status. Brain 146, 1243–1266 (2023). doi: 10.1093/brain/awac436 [doi]
3. Doucette, J., Kames, C. & Rauscher, A. DECAES – DEcomposition and Component Analysis of Exponential Signals. Z Med Phys 30, 271–278 (2020). doi: 10.1016/j.zemedi.2020.04.001 [doi]
4. Fischl, B. FreeSurfer. Neuroimage 62, 774–781 (2012). doi: 10.1016/j.neuroimage.2012.01.021 [doi]
5. Faulkner, M. E. et al. Evidence of association between higher cardiorespiratory fitness and higher cerebral myelination in aging. Proceedings of the National Academy of Sciences 121, (2024). doi: 10.1073/pnas.2402813121 [doi]
6. Hansen, J. et al. Predicted Values for Clinical Exercise Testing. American Review of Respiratory Disease 129, S49 (1984). https://doi.org/10.1164/arrd.1984.129.2P2.S49 [doi]
7. Khodanovich, MY. et al. Global and Regional Sex-Related Differences, Asymmetry, and Peak Age of Brain Myelination in Healthy Adults. Journal of Clinical Medicine, 13 (2024). doi: 10.3390/jcm13237065 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/566-03-006