301-04-003 ISMRM Abstract

Multimodal MRI Framework for Cross-Species Cerebellar Mapping and Atlas Construction in Marmoset, Macaque, and Human.

Primary: Preclinical Animal & in vitro MR - Large Animals, Nonhuman Primates

Secondary: Contrast Mechanisms - Microstructure

301-04-003 · Innovations in Contrast Mechanisms for MRI · Monday, 11 May, 4:10 PM–6:00 PM · Hall 1A

Accepted

Kadharbatcha S Saleem¹, Alexandru V Avram¹, Daniel Glen², Peter J Basser¹

¹Section on Quantitative Imaging and Tissue Sciences (SQITS), Eunice Kennedy Shriver - National Institute of Child Health and Human Development (NICHD), Bethesda, United States of America

²Scientific and Statistical Computing Core, National Institute of Mental Health (NIMH), Bethesda, United States of America

Presenting Author: Mihika Gangolli

Synopsis

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References

1. 1. Özarslan E, Koay CG, Shepherd TM, Komlosh ME, İrfanoğlu MO, Pierpaoli C, Basser PJ. Mean apparent propagator (MAP) MRI: a novel diffusion imaging method for mapping tissue microstructure. Neuroimage. 2013; 78:16-32. 2. Avram A, Sarlls JE, Barnett AS, Özarslan E, Thomas C, Irfanoglu MO, Hutchinson E, Pierpaoli C, Basser PJ. Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure. Neuroimage. 2016; 127:422-434. 3. Tournier JD, Calamante F, Connelly, A. MRtrix: diffusion tractography in crossing fiber regions. International journal of imaging systems and technology. 2012; 22:53-66. 4. Saleem KS, Avram AV, Glen D, Yen CC, Ye FQ, Komlosh M, Basser PJ. High-resolution mapping and digital atlas of subcortical regions in the macaque monkey based on matched MAP-MRI and histology. Neuroimage. 2021; 245:118759. 5. Saleem KS, Avram AV, Yen CC, Magdoom KN, Schram V, Basser PJ (2023). Multimodal anatomical mapping of subcortical regions in Marmoset monkeys using high-resolution MRI and matched histology with multiple stains. Neuroimage. 2023; 281:120311. 6. Fonov V, Evans AC, Botteron K, Almli CR, McKinstry RC, Collins DL, et al. Unbiased average age-appropriate atlases for pediatric studies. Neuroimage. 2011; 54, 313–327. 7. Wang F, Dong Z, Tian Q, Liao C, Fan Q, Hoge WS, Keil B, Polimeni JR, Wald LL, Huang SY, Setsompop K. In vivo human whole-brain Connectom diffusion MRI dataset at 760 μm isotropic resolution. Scientific Data. 2021; 8:1-12. 8. Amunts K, Lepage C, Borgeat L, Mohlberg H, Dickscheid T, Rousseau M, Bludau S, Bazin P, Lewis LB, Oros-Peusquens A, Shah NJ, Lippert T, Zilles K, Evans AC. BigBrain: An Ultrahigh-Resolution 3D Human Brain Model. Science. 2013; 340: 1472-1475. 9. Bizzi A, Brooks RA, Brunetti A, Hill JM, Alger JR, Miletich RS, Francavilla TL, Di Chiro G (1990). Role of iron and ferritin in MR imaging of the brain: a study in primates at different field strengths. Radiology 177: 59-65. 10. Hardy PA, Gash D, Yokel R, Andersen A, Ai Y, Zhang Z (2005). Correlation of R2 with total iron concentration in the brains of rhesus monkeys. J Magn Reson Imaging 21: 118-127.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/301-04-003