Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
564-01-003 ISMRM Abstract

Toward Personalized Blood-Brain Barrier Imaging: Automated Subject-Specific T2 Mapping for Improved Permeability Analysis

Primary: Contrast Mechanisms - Arterial Spin Labelling
Secondary: Contrast Mechanisms - Perfusion
564-01-003 · Perfusion and ASL Imaging: Recent Advances · Wednesday, 13 May, 8:20 AM–9:15 AM · Digital Posters Row E
Keywords: MRI Blood-brain barrier Brain perfusion Arterial Spin Labelling (ASL) Transverse relaxation
Accepted
Amnah Mahroo 1, Matthias Günther2,3,4,5,6, Kamil Uludag7,8,9
1University Health Network, Toronto, Canada
2Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
3Universität Bremen, Bremen, Germany
4mediri GmbH, Heidelberg, Germany
5University Bremen, Bremen, Germany
6University of Bremen, Bremen, Germany
7Krembil Brain Institute, University Health Network, Toronto, Canada
8Department of Physical Sciences, Sunnybrook Research Institute, Toronto, Canada
9Department of Medical Biophysics, University of Toronto, Toronto, Canada
Presenting Author: Amnah Mahroo

Synopsis

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References

1. Atlas SW, editor. Magnetic resonance imaging of the brain and spine. Lippincott Williams & Wilkins; 2009.
2. Mahroo A, Konstandin S, Günther M. Blood–brain barrier permeability to water measured using multiple echo time arterial spin labeling MRI in the aging human brain. Journal of Magnetic Resonance Imaging. 2024 Apr;59(4):1269-82. DOI: 10.1002/jmri.28874 [doi]
3. Mahroo A, Buck MA, Huber J, Breutigam NJ, Mutsaerts HJ, Craig M, Chappell M, Günther M. Robust multi-TE ASL-based blood–brain barrier integrity measurements. Frontiers in neuroscience. 2021 Dec 3;15:719676. DOI: 10.3389/fnins.2021.719676 [doi]
4. Chappell MA, Groves AR, Whitcher B, Woolrich MW. Variational Bayesian inference for a nonlinear forward model. IEEE Transactions on Signal Processing. 2008 Sep 16;57(1):223-36. DOI: 10.1109/TSP.2008.2005752 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/564-01-003