Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
665-01-008 ISMRM Abstract

Hippocampal functional radiomics features for diagnosing cognitively impaired patients with Parkinson's disease

Primary: Neuro - Parkinson's Disease
Secondary: Analysis Methods - Radiomics
665-01-008 · fMRI: Applications in Neurology and Psychiatry I · Thursday, 14 May, 8:30 AM–9:25 AM · Digital Posters Row F
Keywords: fMRI (resting state) Parkinson's Disease Radiomics Cognitive impairment
Accepted
Zeng Wei 1, Xiao Liang1, Jiankun Dai2, Fuqing Zhou1
1The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China
2MR Research, Beijing, China
Presenting Author: Zeng Wei

Synopsis

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References

1. Aarsland D, Batzu L, Halliday GM, et al. Parkinson disease-associated cognitive impairment. Nature Reviews Disease Primers. 2021;7(1):47. doi: 10.1038/s41572-021-00280-3 [doi]
2. Das T, Hwang JJ, Poston KL. Episodic recognition memory and the hippocampus in Parkinson's disease: A review. Cortex. 2019;113:191-209. doi: 10.1016/j.cortex.2018.11.021. [doi]
3. Wylie KP, Kluger BM, Medina LD, et al. Hippocampal, basal ganglia and olfactory connectivity contribute to cognitive impairments in Parkinson's disease. Eur J Neurosci. 2023;57(3):511-26.doi: 10.1111/ejn.15899. [doi]
4. Li K, Su W, Li SH, et al. Resting State fMRI: A Valuable Tool for Studying Cognitive Dysfunction in PD. Parkinsons Dis. 2018;2018:6278649. doi: 10.1155/2018/6278649. [doi]
5. Baggio HC, Junqué C. Functional MRI in Parkinson's Disease Cognitive Impairment. Int Rev Neurobiol. 2019;144:29-58. doi: 10.1016/bs.irn.2018.09.010. [doi]
6. Zarifkar P, Kim J, La C, et al. Cognitive impairment in Parkinson's disease is associated with Default Mode Network subsystem connectivity and cerebrospinal fluid Aβ. Parkinsonism Relat Disord. 2021;83:71-8. doi: 10.1016/j.parkreldis.2021.01.002. [doi]
7. Guo W, Jin W, Li N, et al. Brain activity alterations in patients with Parkinson’s disease with cognitive impairment based on resting-state functional MRI. Neurosci Lett. 2021;747:135672. doi: 10.1016/j.neulet.2021.135672 [doi]
8. Li MG, Bian XB, Zhang J, et al. Aberrant voxel-based degree centrality in Parkinson’s disease patients with mild cognitive impairment. Neurosci Lett. 2021;741:135507. doi: 10.1016/j.neulet.2020.135507. [doi]
9. Chen P, Tang G, Wang Y, et al. Spontaneous brain activity in the hippocampal regions could characterize cognitive impairment in patients with Parkinson's disease. CNS Neuroscience & Therapeutics. 2024;30(4):e14706. doi: 10.1111/cns.14706. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/665-01-008