Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
407-04-008 ISMRM Abstract

Repeatability and Regional Variability of Knee Fatty Acid Composition from CSE-MRI at 3T

Primary: Musculoskeletal - Osteoarthritis
Secondary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others
407-04-008 · New Outcome Measures for Studying the Joint · Tuesday, 12 May, 4:00 PM–5:50 PM · Meeting Room 1.40
Keywords: Osteoarthritis Repeatability Knee Osteoarthritis Chemical Shift-Encoded MRI Fatty acids
Accepted
Dimitri Martel1,2, Anne Adlung 2, Guillaume Madelin2, Thorsten Kirsch3,4, Richard Kijowski5, Amparo Ruiz1,2
1New York University Langone Health, New York, United States of America
2Department of Radiology, New York University Grossman School of Medicine, New York, United States of America
3Department of Orthopedic Surgery, New York University Grossman School of Medicine, New York, United States of America
4New York University Tandon School of Engineering, New York, United States of America
5Department of Radiology, Hospital for Special Surgery, New York, United States of America
Presenting Author: Anne Adlung

Synopsis

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References

1. A. Guermazi, F. Eckstein, D. Hayashi, F.W. Roemer, W. Wirth, T. Yang, J. Niu, L. Sharma, M.C. Nevitt, C.E. Lewis, J. Torner, D.T. Felson, Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively defined cartilage thickness loss in knee osteoarthritis: the Multicenter Osteoarthritis Study, Osteoarthritis Cartilage, 23 (2015) 2191-2198.
2. R. Kijowski, M. Tuite, L. Passov, A. Shimakawa, H. Yu, S.B. Reeder, Cartilage imaging at 3.0T with gradient refocused acquisition in the steady-state (GRASS) and IDEAL fat-water separation, J Magn Reson Imaging, 28 (2008) 167-174.
3. S.M. Eijgenraam, A.S. Chaudhari, M. Reijman, S.M.A. Bierma-Zeinstra, B.A. Hargreaves, J. Runhaar, F.W.J. Heijboer, G.E. Gold, E.H.G. Oei, Time-saving opportunities in knee osteoarthritis: T2 mapping and structural imaging of the knee using a single 5-min MRI scan, European Radiology, 30 (2020) 2231-2240.
4. B. Antony, A. Venn, F. Cicuttini, L. March, L. Blizzard, T. Dwyer, M. Cross, G. Jones, C. Ding, Association of Body Composition and Hormonal and Inflammatory Factors With Tibial Cartilage Volume and Sex Difference in Cartilage Volume in Young Adults, Arthritis Care Res (Hoboken), 68 (2016) 517-525.
5. B. Lü, J.B. Driban, C. Xu, K.L. Lapane, T.E. McAlindon, C.B. Eaton, Dietary Fat Intake and Radiographic Progression of Knee Osteoarthritis: Data From the Osteoarthritis Initiative, Arthritis Care & Research, 69 (2017) 368-375.
6. S. Hada, H. Kaneko, R. Sadatsuki, L. Liu, I. Futami, M. Kinoshita, A. Yusup, Y. Saita, Y. Takazawa, H. Ikeda, K. Kaneko, M. Ishijima, The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: a cross-sectional study, Osteoarthritis and Cartilage, 22 (2014) 1583-1589.
7. S. Emin, E.H.G. Oei, M. Englund, P. Peterson, Imaging-based assessment of fatty acid composition in human bone marrow adipose tissue at 7 T: Method comparison and in vivo feasibility, Magn Reson Med, 90 (2023) 240-249.
8. Y.M. Bastiaansen-Jenniskens, M. Siawash, C.H.A.v.d. Lest, J.A.N. Verhaar, M. Kloppenburg, A.M. Zuurmond, V. Stojanovic‐Susulic, G.J.V.M.v. Osch, S. Clockaerts, Monounsaturated and Saturated, but Not N-6 Polyunsaturated Fatty Acids Decrease Cartilage Destruction Under Inflammatory Conditions, Cartilage, 4 (2013) 321-328.
9. B. Leporq, S.A. Lambert, M. Ronot, V. Vilgrain, B.E. Van Beers, Quantification of the triglyceride fatty acid composition with 3.0 T MRI, NMR Biomed, 27 (2014) 1211-1221.
10. B. Leporq, S.A. Lambert, M. Ronot, I. Boucenna, P. Colinart, F. Cauchy, V. Vilgrain, V. Paradis, B.E. Van Beers, Hepatic fat fraction and visceral adipose tissue fatty acid composition in mice: Quantification with 7.0T MRI, Magn Reson Med, 76 (2016) 510-518.
11. D. Martel, B. Leporq, A. Saxena, H.M. Belmont, G. Turyan, S. Honig, R.R. Regatte, G. Chang, 3T chemical shift-encoded MRI: Detection of altered proximal femur marrow adipose tissue composition in glucocorticoid users and validation with magnetic resonance spectroscopy, J Magn Reson Imaging, 50 (2019) 490-496.
12. D. Martel, B. Leporq, M. Bruno, R.R. Regatte, S. Honig, G. Chang, Chemical shift-encoded MRI for assessment of bone marrow adipose tissue fat composition: Pilot study in premenopausal versus postmenopausal women, Magn Reson Imaging, 53 (2018) 148-155.
13. A. Andersson, C. Nälsén, S. Tengblad, B. Vessby, Fatty acid composition of skeletal muscle reflects dietary fat composition in humans, Am J Clin Nutr, 76 (2002) 1222-1229.
14. F. Isensee, M. Rokuss, L. Krämer, S. Dinkelacker, A. Ravindran, F. Stritzke, B. Hamm, T. Wald, M. Langenberg, C. Ulrich, J. Deissler, R. Floca, K.H. Maier-Hein, nnInteractive: Redefining 3D Promptable Segmentation, ArXiv, abs/2503.08373 (2025).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/407-04-008