Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
560-01-015 ISMRM Abstract

Cross-Modal Correspondence and Divergence between ViSTa Myelin-Weighted Imaging and χ-Diamagnetic Susceptibility Mapping

Accepted
Se-Hong Oh1,2, Ken Sakaie 2,3, Gawon Lee1, Jian Lin2,4, Brian S Appleby5,6, Muralidhar Pallaki7,8, Karin P Mente6,9, Peijun Chen5,10, Jagan Pillai3,11, Mark Lowe2,3,4,12
1Department of Biomedical Engineering, Hankuk university of Foreign Studies, gyeonggi-do, Korea, Republic of
2Diagnostic Radiology, Cleveland Clinic, Cleveland, United States of America
3Cleveland Clinic, Cleveland, United States of America
4Imaging Institute, Cleveland Clinic, Cleveland, United States of America
5Case Western Reserve University School of Medicine, Cleveland, United States of America
6Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, United States of America
7Geriatric Research Education and Clinical Center and Geriatric Medicine, VA Northeast Ohio Healthcare System, Cleveland, United States of America
8Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, United States of America
9Neurology, Case Western Reserve University School of Medicine, Cleveland, United States of America
10Geriatric Research Education and Clinical Center and Psychiatry Service, VA Northeast Ohio Healthcare System, Cleveland, United States of America
11Center for Brain Health, Cleveland Clinic, Cleveland, United States of America
12Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, United States of America
Presenting Author: Ken Sakaie

Synopsis

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References

1. Oh SH, Bilello M, Schindler M, Markowitz CE, Detre JA, Lee J. Direct visualization of short transverse relaxation time component (ViSTa). Neuroimage. 2013;83:485-92. Epub 20130622. doi: 10.1016/j.neuroimage.2013.06.047. PubMed PMID: 23796545; PMCID: PMC3815972. [doi] [pmid]
2. Oh SH, Lee G, Lee J. Three-Dimensional Efficient Myelin-Weighted Imaging Utilizing Direct Visualization of Short Transverse Relaxation Time Component (ViSTa). Hum Brain Mapp. 2025;46(12):e70307. doi: 10.1002/hbm.70307. PubMed PMID: 40844197; PMCID: PMC12371712. [doi] [pmid]
3. Shin HG, Lee J, Yun YH, Yoo SH, Jang J, Oh SH, Nam Y, Jung S, Kim S, Fukunaga M, Kim W, Choi HJ, Lee J. chi-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain. Neuroimage. 2021;240:118371. Epub 20210706. doi: 10.1016/j.neuroimage.2021.118371. PubMed PMID: 34242783. [doi] [pmid]
4. Kim M, Ji S, Kim J, Min K, Jeong H, Youn J, Kim T, Jang J, Bilgic B, Shin HG, Lee J. chi-sepnet: Deep Neural Network for Magnetic Susceptibility Source Separation. Hum Brain Mapp. 2025;46(2):e70136. doi: 10.1002/hbm.70136. PubMed PMID: 39835664; PMCID: PMC11748151. [doi] [pmid]
5. Kim J, Kim M, Ji S, Min K, Jeong H, Shin HG, Oh C, Fox RJ, Sakaie KE, Lowe MJ, Oh SH, Straub S, Kim SG, Lee J. In-vivo high-resolution chi-separation at 7T. Neuroimage. 2025;308:121060. Epub 20250128. doi: 10.1016/j.neuroimage.2025.121060. PubMed PMID: 39884410. [doi] [pmid]
6. Lee J, Hyun JW, Lee J, Choi EJ, Shin HG, Min K, Nam Y, Kim HJ, Oh SH. So You Want to Image Myelin Using MRI: An Overview and Practical Guide for Myelin Water Imaging. J Magn Reson Imaging. 2021;53(2):360-73. Epub 20200203. doi: 10.1002/jmri.27059. PubMed PMID: 32009271. [doi] [pmid]
7. Lee J, Ji S, Oh SH. So You Want to Image Myelin Using MRI: Magnetic Susceptibility Source Separation for Myelin Imaging. Magn Reson Med Sci. 2024;23(3):291-306. Epub 20240420. doi: 10.2463/mrms.rev.2024-0001. PubMed PMID: 38644201; PMCID: PMC11234950. [doi] [pmid]

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