461-01-010 ISMRM Abstract

Cardiac Phase-Resolved Simultaneous T1 and T2* Mapping in Rodent Hearts

Primary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI

Secondary: Cardiovascular - Myocardium

461-01-010 · Cardiac Tissue Characterization · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row B

Accepted

Shahriar Shalikar ^1,2, Jose Raul Velasquez Vides^1,3, Mostafa Berangi¹, Alexis Jouenne⁴, Yuheng Huang⁵, Thomas Gladytz¹, Jason M Millward^1,6, Hsin-Jung Yang⁵, Thoralf Niendorf^1,6,7, Frank Kober⁴, Min-Chi Ku^1,7

¹Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), Berlin, Germany

²Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

³Institute for Medical Engineering, Otto von Guericke University, Magdeburg, Germany

⁴Aix-Marseille Univ, CNRS, CRMBM, Centre de Résonance Magnétique Biologique et Médicale, Marseille, France

⁵Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, United States of America

⁶Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine, Berlin, Germany

⁷DZHK (German Centre for Cardiovascular Research), Berlin, Germany

Presenting Author: Shahriar Shalikar

Synopsis

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References

1. M. Heilmann et al., "Simultaneous dynamic T 1 and T 2* measurement for AIF assessment combined with DCE MRI in a mouse tumor model," Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 20, pp. 193-203, 2007.

2. G. J. Lima da Cruz, C. Velasco, B. Lavin, O. Jaubert, R. M. Botnar, and C. Prieto, "Myocardial T1, T2, T2*, and fat fraction quantification via low‐rank motion‐corrected cardiac MR fingerprinting," Magnetic Resonance in Medicine, vol. 87, no. 6, pp. 2757-2774, 2022.

3. I. Hermann, P. Kellman, O. B. Demirel, M. Akçakaya, L. R. Schad, and S. Weingärtner, "Free‐breathing simultaneous T1, T2, and T2∗ quantification in the myocardium," Magnetic resonance in medicine, vol. 86, no. 3, pp. 1226-1240, 2021.

4. T. Cao et al., "Free‐breathing, non‐ECG, simultaneous myocardial T1, T2, T2*, and fat‐fraction mapping with motion‐resolved cardiovascular MR multitasking," Magnetic Resonance in Medicine, vol. 88, no. 4, pp. 1748-1763, 2022.

5. H. Zhang, Q. Ye, J. Zheng, E. B. Schelbert, T. K. Hitchens, and C. Ho, "Improve myocardial T1 measurement in rats with a new regression model: application to myocardial infarction and beyond," Magnetic resonance in medicine, vol. 72, no. 3, pp. 737-748, 2014.

6. O. Laghzali et al., "Cardiac Phase-Resolved T2* Magnetic Resonance Imaging Reveals Differences Between Normal Hearts and a Humanized Mouse Model of Hypertrophic Cardiomyopathy," Biomedicines, vol. 13, no. 5, p. 1193, 2025.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/461-01-010