Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
505-02-005 ISMRM Abstract

Longitudinal structural and functional remodeling of brain networks in treatment-resistant depression with SCC DBS

Primary: Neuro - Neuromodulation
Secondary: Neuro - Psychiatric Disorders
505-02-005 · Insights into Psychiatric Disorders and the Human Connectome · Wednesday, 13 May, 8:20 AM–10:10 AM · Ballroom West
Keywords: Deep Brain Stimulation Depression Neural network remodeling Subcallosal cingulate
Accepted
JungHo Cha1, Ha Neul Song1, Martijn Figee1, Patricio Riva-Posse2, Brian H Kopell1,3,4, Jaemin Shin 5,6, Suchandrima Banerjee7, Helen S Mayberg8, Ki Sueng Choi1
1Nash Family Center for Advanced Circuit Therapeutics, Icahn School of Medicine at Mount Sinai, New York, United States of America
2Emory University School of Medicine, Atlanta, United States of America
3Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, United States of America
4Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, United States of America
5GE HealthCare, San Ramon, United States of America
6GE HealthCare., NY, United States of America
7GE HealthCare Global MR Applications & Workflow, Menlo Park, United States of America
8Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States of America
Presenting Author: Jaemin Shin

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, Schwalb JM, Kennedy SH. Deep brain stimulation for treatment-resistant depression. Neuron. 2005;45(5):651-60. Epub 2005/03/08. doi: 10.1016/j.neuron.2005.02.014. PubMed PMID: 15748841. [doi] [pmid]
2. Boutet A, Chow CT, Narang K, Elias GJB, Neudorfer C, Germann J, Ranjan M, Loh A, Martin AJ, Kucharczyk W, Steele CJ, Hancu I, Rezai AR, Lozano AM. Improving Safety of MRI in Patients with Deep Brain Stimulation Devices. Radiology. 2020;296(2):250-62. Epub 2020/06/24. doi: 10.1148/radiol.2020192291. PubMed PMID: 32573388; PMCID: PMC7543718. [doi] [pmid]
3. Elias GJB, Germann J, Boutet A, Loh A, Li B, Pancholi A, Beyn ME, Naheed A, Bennett N, Pinto J, Bhat V, Giacobbe P, Woodside DB, Kennedy SH, Lozano AM. 3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation. Brain. 2022;145(6):2214-26. Epub 2021/12/18. doi: 10.1093/brain/awab447. PubMed PMID: 34919630. [doi] [pmid]
4. Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH. Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry. 2008;64(6):461-7. Epub 2008/07/22. doi: 10.1016/j.biopsych.2008.05.034. PubMed PMID: 18639234. [doi] [pmid]
5. Cha J, Choi KS, Rajendra JK, McGrath CL, Riva-Posse P, Holtzheimer PE, Figee M, Kopell BH, Mayberg HS. Whole brain network effects of subcallosal cingulate deep brain stimulation for treatment-resistant depression. Mol Psychiatry. 2023. Epub 2023/11/03. doi: 10.1038/s41380-023-02306-6. PubMed PMID: 37919403. [doi] [pmid]
6. Fischl B. FreeSurfer. Neuroimage. 2012;62(2):774-81. Epub 2012/01/18. doi: 10.1016/j.neuroimage.2012.01.021. PubMed PMID: 22248573; PMCID: PMC3685476. [doi] [pmid]
7. Jenkinson M, Beckmann CF, Behrens TE, Woolrich MW, Smith SM. Fsl. Neuroimage. 2012;62(2):782-90. Epub 2011/10/08. doi: 10.1016/j.neuroimage.2011.09.015. PubMed PMID: 21979382. [doi] [pmid]
8. Cox RW. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res. 1996;29(3):162-73. Epub 1996/06/01. doi: 10.1006/cbmr.1996.0014. PubMed PMID: 8812068. [doi] [pmid]
9. Yeo BT, Krienen FM, Sepulcre J, Sabuncu MR, Lashkari D, Hollinshead M, Roffman JL, Smoller JW, Zollei L, Polimeni JR, Fischl B, Liu H, Buckner RL. The organization of the human cerebral cortex estimated by intrinsic functional connectivity. J Neurophysiol. 2011;106(3):1125-65. Epub 2011/06/10. doi: 10.1152/jn.00338.2011. PubMed PMID: 21653723; PMCID: PMC3174820. [doi] [pmid]
10. Schaefer A, Kong R, Gordon EM, Laumann TO, Zuo XN, Holmes AJ, Eickhoff SB, Yeo BTT. Local-Global Parcellation of the Human Cerebral Cortex from Intrinsic Functional Connectivity MRI. Cereb Cortex. 2018;28(9):3095-114. Epub 2017/10/06. doi: 10.1093/cercor/bhx179. PubMed PMID: 28981612; PMCID: PMC6095216. [doi] [pmid]
11. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O, Cader MZ, Matthews PM, Behrens TE. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage. 2006;31(4):1487-505. Epub 2006/04/21. doi: 10.1016/j.neuroimage.2006.02.024. PubMed PMID: 16624579. [doi] [pmid]
12. Zang YF, He Y, Zhu CZ, Cao QJ, Sui MQ, Liang M, Tian LX, Jiang TZ, Wang YF. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev. 2007;29(2):83-91. Epub 2006/08/22. doi: 10.1016/j.braindev.2006.07.002. PubMed PMID: 16919409. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/505-02-005