Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
464-01-013 ISMRM Abstract

Skeletal muscle characterisation with a diffusion-relaxation model, and implications for perfusion fraction estimation

Accepted
Matteo Figini 1, Paddy Slator2,3, Eleftheria Panagiotaki1, Giovanna Rizzo4, Alfonso Mastropietro4
1Hawkes Institute, Department of Computer Science, University College London, London, United Kingdom
2CUBRIC, Cardiff University, Cardiff, United Kingdom
3School of Computer Science and Informatics, Cardiff University, Cardiff, United Kingdom
4Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato, Consiglio Nazionale delle Ricerche, Milano, Italy
Presenting Author: Matteo Figini

Synopsis

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References

1. Mastropietro, A.; Porcelli, S.; Cadioli, M.; Rasica, L.; Scalco, E.;, Gerevini, S.; ... & Rizzo, G. (2018). Triggered intravoxel incoherent motion MRI for the assessment of calf muscle perfusion during isometric intermittent exercise. NMR in Biomedicine, 31(6): e3922.
2. Oudeman, J.; Nederveen, A. J.; Strijkers, G. J.; Maas, M.; Luijten, P. R.; & Froeling, M. (2016). Techniques and applications of skeletal muscle diffusion tensor imaging: a review. Journal of Magnetic Resonance Imaging, 43(4): 773-788.
3. Bonny, J. M.; Zanca, M.; Boespflug-Tanguy; O., Dedieu, V.; Joandel, S.; & Renou, J. P. (1998). Characterization in vivo of muscle fiber types by magnetic resonance imaging. Magnetic resonance imaging, 16(2): 167-173.
4. Mastropietro, A., Peruzzo, D., Taccogna, M. G., Sanna, N., Casali, N., Nossa, R., ... & Rizzo, G. (2025). Multiparametric MRI assessment of morpho-functional muscle changes following a 6-month fes-cycling training program: pilot study in people with a complete spinal cord injury. JMIR Rehabilitation and Assistive Technologies, 12, e64825.
5. Figini, M.; Slator, P.J.; Rizzo, G.; Mastropietro, A. (2024). Combined Diffusion-Relaxation MRI to Assess Muscle Microstructure and Composition. Proc. Intl. Soc. Mag. Reson. Med. 32 (2024): 900
6. Marty, B., Baudin, P.-Y., Reyngoudt, H., Azzabou, N., Araujo, E. C. A., Carlier, P. G., and de Sousa, P. L. (2016) Simultaneous muscle water T2 and fat fraction mapping using transverse relaxometry with stimulated echo compensation. NMR Biomed., 29: 431–443.
7. Yao, L.; Yip, A.L.; Shrader, J. A.; Mesdaghinia, S.; Volochayev, R.; Jansen, A.V.; Miller, F.W.; Rider, L.G. Magnetic resonance measurement of muscle T2, fat-corrected T2 and fat fraction in the assessment of idiopathic inflammatory myopathies (2016), Rheumatology, 55(3): 441–449
8. Lu, H. and Ge, Y. (2008), Quantitative evaluation of oxygenation in venous vessels using T2-Relaxation-Under-Spin-Tagging MRI. Magn. Reson. Med., 60: 357-363

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