Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
552-03-011 / 552-03-011 ISMRM Abstract

Impact of Free Water in the Assessment of Periventricular Flow as Revealed in Wilson’s Disease

Primary: Analysis Methods - Data Processing
Secondary: Diffusion - Diffusion Analysis & Visualization
552-03-011 · Diffusion Methodologies and Clinical Applications · Wednesday, 13 May, 4:00 PM–5:36 PM · Power Pitch Theatre 2
552-03-011 · Diffusion Methodologies and Clinical Applications · Wednesday, 13 May, 4:00 PM–5:36 PM · Power Pitch Theatre 2
Keywords: Free water DTI-ALPS Wilson Disease Glymphatic system (GS)
Accepted
Gaiying Li 1,2, Siyuan Fang1,2, Yupeng Wu1,2, Xiangzhen Yuan3, Ying Tang1,2, Xiaozhong Jing4, Xu Yan5, Yang Song5, Xiaoping Wang6, Jianqi Li1,2
1Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China
2Institute of Magnetic Resonance and Molecular Imaging in Medicine, East China Normal University, Shanghai, China
3Department of Neurology, Weifang People's Hospital, Shandong Second Medical University, Weifang, China
4The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China
5MR Research Collaboration, Shanghai, China
6Department of Radiology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital, Shanghai, China
Presenting Author: Gaiying Li

Synopsis

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References

1. Taoka T, Masutani Y, Kawai H, et al. Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases. Jpn J Radiol. 2017;35:172-178.doi:10.1007/s11604-017-0617-z [doi]
2. Li S, Chen R, Cao Z, et al. Microstructural Bias in the Assessment of Periventricular Flow as Revealed in Postmortem Brains. Radiology. 2025;316:e250753.doi:10.1148/radiol.250753 [doi]
3. Taoka T, Ito R, Nakamichi R, Nakane T, Kawai H, Naganawa S. Diffusion Tensor Image Analysis ALong the Perivascular Space (DTI-ALPS): Revisiting the Meaning and Significance of the Method. Magn Reson Med Sci. 2024;23:268-290.doi:10.2463/mrms.rev.2023-0175 [doi]
4. Hsu JL, Wei YC, Toh CH, et al. Magnetic Resonance Images Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction in Alzheimer Disease. Ann Neurol. 2023;93:164-174.doi:10.1002/ana.26516 [doi]
5. Siow TY, Toh CH, Hsu JL, et al. Association of sleep, neuropsychological performance, and gray matter volume with glymphatic function in community-dwelling older adults. Neurology. 2022;98:e829-e838.doi:10.1212/WNL.0000000000013215 [doi]
6. Taoka T, Masutani Y, Kawai H, et al. Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases. Jpn J Radiol. 2017;35:172-178.doi:10.1007/s11604-017-0617-z [doi]
7. Zhang WH, Zhou Y, Wang JN, et al. Glymphatic clearance function in patients with cerebral small vessel disease. Neuroimage. 2021;238:118257.doi:10.1016/j.neuroimage.2021.118257 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/552-03-011