Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
367-05-012 ISMRM Abstract

SUPREME-SWI-FLAIR Enhances Central Vein Sign (CVS) Detection for MS at 3T MRI

Primary: Neuro - Multiple Sclerosis
Secondary: Contrast Mechanisms - Susceptibility/QSM
367-05-012 · Neuroinflammation: Myelin and Iron · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row H
Keywords: Multiple Sclerosis Ultra-high resolution Susceptibility-weighted Imaging 3T Central Vein Sign
Accepted
Vivian B Truong1,2, Fen Bao1, Sarah J Wright1, Sara Omar1, Anas Nourelden1, Anza B Memon1, Yongsheng Chen 2,3
1Department of Neurology, Wayne State University School of Medicine, Detroit, United States of America
2Department of Biomedical Engineering, Wayne State University, Detroit, United States of America
3Wayne State University School of Medicine, Detroit, United States of America
Presenting Author: Yongsheng Chen

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References

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2. Anan RA, El-Adalany MA, Belal TMI, Elmogy SAE-D. Detection of central veins using susceptibility weighted imaging (SWI) for discrimination between lesions in multiple sclerosis (MS) and cerebral small vessel disease (CSVD). Egyptian Journal of Radiology and Nuclear Medicine. 2020;51(1). https://doi.org/10.1186/s43055-020-00185-3 [doi]
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7. Truong V, Sawan H, Wright S, Chen Y. SUPREME: Susceptibility with Ultra-high-resolution Parallel REconstruction of Multi-Echo. Paper presented at: Proc. Intl. Soc. Mag. Reson. Med. (ISMRM25); May 10, 2025, 2025; Honolulu, HI.
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9. Al-Louzi O, Manukyan S, Donadieu M, et al. Lesion size and shape in central vein sign assessment for multiple sclerosis diagnosis: An in vivo and postmortem MRI study. Mult Scler. 2022;28(12):1891-1902. https://doi.org/10.1177/13524585221097560 [doi]
10. Absinta M, Nair G, Monaco MCG, et al. The "central vein sign" in inflammatory demyelination: The role of fibrillar collagen type I. Ann Neurol. 2019;85(6):934-942. https://doi.org/10.1002/ana.25461 [doi]
11. Tan LvS, Ronald; Pouwels, Petra; van Walderveen, Marianne; Reichenbach, Juergen; Manoliu, Radu; Barkhof, Frederik. MR Venography of Multiple Sclerosis AJNR Am J Neuroradiol. 2000;21:1039-1042. PMID: 10871010 [pmid]
12. Maggi P, Absinta M, Sati P, et al. The "central vein sign" in patients with diagnostic "red flags" for multiple sclerosis: A prospective multicenter 3T study. Mult Scler. 2020;26(4):421-432. https://doi.org/10.1177/1352458519876031 [doi]
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http://echo.ismrm.org/p/ISMRM2026/367-05-012