Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-05-010 ISMRM Abstract

Feasibility of Ultra-High field MRI for assessing small artery structure and haemodynamics in children

Primary: Pediatrics - Neuro
Secondary: Neuro - Blood Vessels
461-05-010 · Advances in Neuroimaging and Biomarkers for Brain Health and Disease · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row B
Keywords: Magnetic resonance angiography Cerebral blood flow Ultra high field MRI Paediatric neuroimaging Lenticulostriate arteries
Accepted
Ioana Pinzaru 1,2,3, Anthony Price2,3, Alan Wright3, Philippa Bridgen2,4,5, Pierluigi Di Cio2,4,5, Inka Granlund2,4,5, Lucy Billimoria2,4,5, Sharon L Giles2,5, Ming Lim6, Maria Zuluaga2,7, Jon O Cleary8, Andrew MacKinnon9, Chinedu Maduakor10, Henry Mandeville11, Ugochi Akerele2, Shaihan Malik2, Jonathan O'Muircheartaigh2,12, David Carmichael2, Saras Sabanathan6, Samah Babiker13, Philip Benjamin2,9, Jon O Cleary2,14
1Medical Physics, King's College Hospital NHS Foundation Trust London, London, United Kingdom
2School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
3Medical Physics and Clinical Engineering, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
4London Collaborative Ultra-High field System (LoCUS), King's College London, London, United Kingdom
5Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
6Childrens’ Neurosciences, Evelina Children’s Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
7EURECOM, Biot, France
8The Sickle FES Charity, London, United Kingdom
9Department of Neuroradiology, St George’s University Hospitals NHS Foundation Trust, London, United Kingdom
10St George’s University Hospitals NHS Foundation Trust, London, United Kingdom
11The Royal Marsden Hospital and Institute of Cancer Research, Sutton, United Kingdom
12Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom
13Department of Paediatric Haematology, Evelina Children’s Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
14Department of Radiology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
Presenting Author: Ioana Pinzaru

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References

1. Marinkovic, S., Gibo, H., Milisavljevic, M., & Cetkovic, M. (2001). Anatomic and clinical correlations of the lenticulostriate arteries. Clinical anatomy (New York, N.Y.), 14(3), 190–195. https://doi.org/10.1002/ca.1032 [doi]
2. Osuafor, Christopher et al. (2022). Visualisation of lenticulostriate arteries using contrast-enhanced time-of-flight magnetic resonance angiography at 7 Tesla. Scientific Reports. 12. doi:10.1038/s41598-022-24832-z. [doi]
3. Sergio Valencia, Fedel Machado-Rivas, Maria Camila Cortes-Albornoz, Samuel CD Cartmell, Harry Griffin, Darren B. Orbach, Vanessa Rameh, Alfred Pokmeng See, Simon K. Warfield, Onur Afacan, Camilo Jaimes. 7 Tesla Time-of-Flight MRA in Adolescents. American Journal of Neuroradiology Jul 2025, ajnr.A8908; doi:10.3174/ajnr.A8908 [doi]
4. Yoon S, Park SH, Han D. Uncover This Tech Term: Compressed Sensing Magnetic Resonance Imaging. Korean J Radiol. 2023 Dec;24(12):1293-1302. doi: 10.3348/kjr.2023.0743. PMID: 38016687; PMCID: PMC10700992 [doi] [pmid]
5. Meixner, C. R., Liebig, P., Speier, P., Forman, C., Hensel, B., Schmidt, M., Saake, M., Uder, M., Doerfler, A., Heidemann, R. M., Schmitter, S., & Nagel, A. M. (2019). High resolution time-of-flight MR-angiography at 7 T exploiting VERSE saturation, compressed sensing and segmentation. Magnetic resonance imaging, 63, 193–204. https://doi.org/10.1016/j.mri.2019.08.014 [doi]
6. Lakhani, D. A., Zhou, X., Tao, S., Westerhold, E. M., Eidelman, B. H., Singh Sandhu, S. J., & Middlebrooks, E. H. (2023). Clinical application of ultra-high resolution compressed sensing time-of-flight MR angiography at 7T to detect small vessel pathology. The neuroradiology journal, 36(3), 335–340. https://doi.org/10.1177/19714009221129576 [doi]
7. Marieke van den Kerkhof, Jacobus F.A. Jansen, Robert J. van Oostenbrugge, Walter H. Backes, 1D versus 3D blood flow velocity and pulsatility measurements of lenticulostriate arteries at 7T MRI,Magnetic Resonance Imaging, Volume 96, 2023, Pages 144-150, ISSN 0730-725X, https://doi.org/10.1016/j.mri.2022.12.005. [doi]
8. Lovett ME, O'Brien NF. Transcranial Doppler Ultrasound, a Review for the Pediatric Intensivist. Children (Basel). 2022 May 16;9(5):727. doi: 10.3390/children9050727. PMID: 35626904; PMCID: PMC9171581. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/461-05-010