Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
430-02-009 ISMRM Abstract

Open-source sequence implementation for 31P magnetization transfer MRS within the Pulseq framework

Primary: Contrast Mechanisms - Non-Proton
Secondary: Acquisition & Reconstruction - Open source software, sequences, and reconstruction algorithms
430-02-009 · Novel Acquisition Strategies and Open-Source Sequences · Tuesday, 12 May, 8:20 AM–10:10 AM · Meeting Room 2.60
Keywords: Magnetization transfer Phosphorous Magnetic Resonance Spectroscopy Pulseq Pulse sequence developoment
Accepted
Bela Seng 1,2, Justyna Platek1,2,3, Marcel Awenius1,2, Jan-Philipp Schmitz1,2, Peter Bachert1,2, Mark E Ladd1,2,4, Andreas Korzowski1, Vanessa L Franke1
1Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
2Faculty of Physics and Astronomy, Heidelberg University, Heidelberg, Germany
3International Max Planck Research School for Quantum Dynamics in Physics, Chemistry, and Biology, MPIK, Heidelberg, Germany
4Faculty of Medicine, Heidelberg University, Heidelberg, Germany
Presenting Author: Bela Seng

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References

1. Petersen, Kitt Falk, et al. "Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes." New England Journal of Medicine 350.7 (2004): 664-671. http://doi.org/10.1056/NEJMoa031314 [doi]
2. Petersen, Kitt Falk, et al. "Mitochondrial dysfunction in the elderly: possible role in insulin resistance." Science 300.5622 (2003): 1140-1142. http://doi.org/10.1126/science.1082889 [doi]
3. Layton, Kelvin J., et al. "Pulseq: a rapid and hardware‐independent pulse sequence prototyping framework." Magnetic resonance in medicine 77.4 (2017): 1544-1552. http://doi.org/10.1002/mrm.26235 [doi]
4. Ren, Jimin, A. Dean Sherry, and Craig R. Malloy. "Amplification of the effects of magnetization exchange by 31P band inversion for measuring adenosine triphosphate synthesis rates in human skeletal muscle." Magnetic resonance in medicine 74.6 (2015): 1505-1514. https://doi.org/10.1002/mrm.25514 [doi]
5. Ren, Jimin, A. Dean Sherry, and Craig R. Malloy. "Modular 31P wideband inversion transfer for integrative analysis of adenosine triphosphate metabolism, T1 relaxation and molecular dynamics in skeletal muscle at 7T." Magnetic resonance in medicine 81.6 (2019): 3440-3452. https://doi.org/10.1002/mrm.27686 [doi]
6. Awenius M, Abeln H, Müller M, et al. Three-dimensional radial echo-planar spectroscopic imaging for hyperpolarized 13C MRSI in vivo. Magnetic resonance in medicine 2025; 93(1): 31-41. doi: 10.1002/mrm.30258 [doi]
7. Ludwig D, Korzowski A, Ruhm L, Ladd ME, and Bachert P. Three–dimensional 31P radial echo–planar spectroscopic imaging in vivo at 7T. Proc ISMRM 25: 1247.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/430-02-009