Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
463-05-003 ISMRM Abstract

DCE-MRI Identifies Responders: Post-Ktrans Outperforms in Predicting Pathologic Complete Response in Esophageal Carcinoma

Primary: Analysis Methods - Classification and Prediction
Secondary: Body - Chest/Thorax
463-05-003 · Malignant Tumor in the Body · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row D
Keywords: 3.0T magnetic resonance imaging Efficacy prediction DCE Functional Parameters
Accepted
Jinrong Qu 1,2, Zihan Wang1,2, Funing Chu1,2, MENGZHU WANG3, Robert Grimm4, Wenshi Li1,2
1Radiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China
2HNHC Key Laboratory of Oncology Medical Imaging Response Assessment, Zhengzhou, China
3MR Research Collaboration Team, Siemens Healthineers Ltd., Beijing, China
4Research & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany
Presenting Author: Jinrong Qu

Synopsis

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References

1. Orton MR, d'Arcy JA, Walker-Samuel S, et al. Computationally efficient vascular input function models for quantitative kinetic modelling using DCE-MRI. Phys Med Biol. 2008. 53(5): 1225-39. doi: 10.1088/0031-9155/53/5/005 [doi]
2. Parker GJM, Roberts C, Macdonald A, et al. Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI. Magn Reson Med. 2006. 56(5): 993-1000. doi: 10.1002/mrm.21066 [doi]
3. Lau D, McLean MA, Priest AN, et al. Multiparametric MRI of early tumor response to immune checkpoint blockade in metastatic melanoma. J Immunother Cancer. 2021. 9(9). doi: 10.1136/jitc-2021-003125 [doi]
4. Sun N, Ge X, Liu X, Xu L. Histogram analysis of DCE-MRI for chemoradiotherapy response evaluation in locally advanced esophageal squamous cell carcinoma. Radiol Med. 2020. 125(2): 165-176. doi: 10.1007/s11547-019-01081-1 [doi]
5. McDonnell CO, Bouchier-Hayes DJ, Toomey D, et al. Effect of neoadjuvant chemoradiotherapy on angiogenesis in oesophageal cancer. Br J Surg. 2003. 90(11): 1373-8. doi: 10.1002/bjs.4338 [doi]
6. Li C, Zhao S, Zheng Y, et al. Preoperative pembrolizumab combined with chemoradiotherapy for oesophageal squamous cell carcinoma (PALACE-1). Eur J Cancer. 2021. 144: 232-241. doi: 10.1016/j.ejca.2020.11.039 [doi]

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http://echo.ismrm.org/p/ISMRM2026/463-05-003