Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
652-02-014 / 652-02-014 ISMRM Abstract

Heart–Brain Interactions in Chronic Heart Failure: Linking Cardiac Dysfunction to Cognitive Decline

Primary: Brain Function and fMRI - fMRI Analysis
Secondary: Cardiovascular - Heart Failure
652-02-014 · Heart and Brain Interactions · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
652-02-014 · Heart and Brain Interactions · Thursday, 14 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2
Keywords: fMRI (resting state) Heart Failure Cerebrovascular reactivity Cognitive impairments Heart-brain axis
Accepted
Qihui Wang 1, Xiuqin Jia2,3,4,5, Qi Yang3,4,5,6,7
1radiology, Beijing Chaoyang Hospital, Capital Medical University, beijing, China
2Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
3Beijing Chaoyang Hospital, Capital Medical University, beijing, China
4Department of Radiology, Beijing Chao-Yang Hospital, Beijing, China
5Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, beijing, China
6Key Laboratory of Medical Engineering for Cardiovascular Disease, Ministry of Education, Beijing, China
7Laboratory for Clinical Medicine, Capital Medical University, Beijing, China
Presenting Author: Qihui Wang
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References

1. Testai FD., Gorelick PB., Chuang P-Y., et al. Cardiac Contributions to Brain Health: A Scientific Statement From the American Heart Association. Stroke 2024. Doi: 10.1161/str.0000000000000476. [doi]
2. Angermann CE., Frey A., Ertl G. Cognition matters in cardiovascular disease and heart failure. Eur Heart J 2012;33(14):1721–3. Doi: 10.1093/eurheartj/ehs128. [doi]
3. Valenza G., Matić Z., Catrambone V. The brain–heart axis: integrative cooperation of neural, mechanical and biochemical pathways. Nat Rev Cardiol 2025. Doi: 10.1038/s41569-025-01140-3. [doi]
4. Roy B., Woo MA., Wang DJJ., et al. Reduced regional cerebral blood flow in patients with heart failure. European J of Heart Fail 2017;19(10):1294–302. Doi: 10.1002/ejhf.874. [doi]
5. Ting Liu Y., Ting Yang Y., Xiang Tang C., et al. Brain structural and functional changes in patients with chronic heart failure. Neuroscience 2024;565:148–54. Doi: 10.1016/j.neuroscience.2024.11.060. [doi]
6. Liu P., Li Y., Pinho M., et al. Cerebrovascular reactivity mapping without gas challenges. Neuroimage 2017;146:320–6. Doi: 10.1016/j.neuroimage.2016.11.054. [doi]
7. Morse CJ., Luchkanych AMS., Boyes NG., et al. Cardiac dysfunction is associated with indices of brain atrophy and cognitive impairment in heart failure with reduced ejection fraction. J Appl Physiol 2025. Doi: 10.1152/japplphysiol.00840.2024. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/652-02-014