361-06-013 ISMRM Abstract

Study of MT-induced T1 differences between normal controls and mild traumatic brain injury patients

Primary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI

Secondary: Neuro - Traumatic Brain Injury

361-06-013 · Quantitative Imaging: Head and Neck II · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row B

Keywords: T1 relaxation time MP2RAGE MTBI Magnetization transfer (MT) DSIR

Accepted

Mark Bydder ¹, Paul M Condron^1,2, Olivier M Girard^3,4, Tracy R Melzer^2,5,6,7, Daniel Cornfeld^1,2, Maryam Tayebi^1,8, Eryn Kwon^1,8, Gil Newburn¹, Samantha Holdsworth^1,2,8, Graeme M Bydder^1,9

¹Mātai Medical Research Institute, Gisborne, New Zealand

²University of Auckland, Auckland, New Zealand

³Aix Marseille Univ, Marseille, France

⁴APHM, Hôpital Universitaire Timone, CEMEREM, Marseille, France

⁵School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand

⁶University of Otago, Christchurch, New Zealand

⁷University of Canterbury, Christchurch, New Zealand

⁸Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

⁹University of California, Berkeley, United States of America

Presenting Author: Mark Bydder

Synopsis

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References

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4. Kim SY, Yeh PH, Ollinger JM et al. Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms. Transl Psychiatry 2023;13:289

5. Newburn G, McGeown JP, Kwon EE, Tayebi M, Condron P, Emsden T, Holdsworth SJ, Cornfeld DM, Bydder GM. Targeted MRI of small increases in the T1 of normal appearing white matter in mild traumatic brain injury using a divided subtracted inversion recovery sequence. OBM Neurobiol 2023;7:201

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14. Bydder M, Ali F, Condron P, et al. Validation of an ultrahigh contrast divided subtracted inversion recovery technique using a standard T1 phantom. NMR Biomed. 2024;37(12):e5269. doi:10.1002/nbm.5269 [doi]

15. Bydder M, Girard OM, Melzer TR, et al. The Role of Incidental Magnetization Transfer in Divided Subtracted Inversion Recovery. NMR Biomed. 2025;38(12):e70165. doi:10.1002/nbm.70165 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/361-06-013