Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
351-02-011 / 351-02-011 ISMRM Abstract

Radiomics analysis of clinical knee MRI associates with radiographic and symptomatic PTOA 10 years after ACL reconstruction

Primary: Musculoskeletal - Osteoarthritis
Secondary: Analysis Methods - Radiomics
351-02-011 · MSK: Everything, Everywhere, and All at Once · Monday, 11 May, 1:50 PM–3:26 PM · Power Pitch Theatre 1
351-02-011 · MSK: Everything, Everywhere, and All at Once · Monday, 11 May, 1:50 PM–3:26 PM · Power Pitch Theatre 1
Keywords: Clinical application Machine learning Knee Osteoarthritis Clinic Patient MR Imaging Radiomics analysis
Accepted
Kihwan Kim 1,2,3, Urmika Gosh2, Sameed Khan1,2,3, Richard Lartey1,2, Brendan Eck1,3, Mei Li1,2, Mingrui Yang1,2, Jeehun Kim1,2,3, Carl Winalski1,2,3, Faysal Althahawi1,3, Nancy Obuchowski1,4, Morgan H Jones5, Laura J Huston6, Kevin D Harkins6, Michael V Knopp7, Christopher C Kaeding8, Kurt P Spindler1,9, Xiaojuan Li1,2,3
1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, United States of America
2Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, United States of America
3Department of Diagnostic Radiology, Diagnostics Institute, Cleveland Clinic, Cleveland, United States of America
4Department of Quantitative Health Science, Lerner Research Institute, Cleveland Clinic, Cleveland, United States of America
5Department of Orthopaedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America
6Radiology and Radiological Sciences, Vanderbilt University, Nashville, United States of America
7The Ohio State University, Columbus, United States of America
8Department of Orthopaedic Surgery, The Ohio State University, Columbus, United States of America
9Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, United States of America
Presenting Author: Kihwan Kim

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References

1. Kaeding, C. C., Léger-St-Jean, B. & Magnussen, R. A. Epidemiology and Diagnosis of Anterior Cruciate Ligament Injuries. Clin. Sports Med. 36, 1–8 (2017).
2. Barenius, B. et al. Increased Risk of Osteoarthritis After Anterior Cruciate Ligament Reconstruction: A 14-Year Follow-up Study of a Randomized Controlled Trial. Am. J. Sports Med. 42, 1049–1057 (2014).
3. Ehmig, J. et al. MR-Imaging in Osteoarthritis: Current Standard of Practice and Future Outlook. Diagn. Basel Switz. 13, 2586 (2023).
4. Jiang, T. et al. Radiomics signature of osteoarthritis: Current status and perspective. J. Orthop. Transl. 45, 100–106 (2024).
5. Wasserstein, D. et al. KOOS pain as a marker for significant knee pain two and six years after primary ACL reconstruction: a Multicenter Orthopaedic Outcomes Network (MOON) prospective longitudinal cohort study. Osteoarthritis Cartilage 23, 1674–1684 (2015).
6. Yang, M. et al. Automated knee cartilage segmentation for heterogeneous clinical MRI using generative adversarial networks with transfer learning. Quant. Imaging Med. Surg. 12, 2620–2633 (2022).
7. Chirra, P. et al. Multisite evaluation of radiomic feature reproducibility and discriminability for identifying peripheral zone prostate tumors on MRI. J. Med. Imaging 6, 1 (2019).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/351-02-011