Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
667-02-001 ISMRM Abstract

Investigating the effects of spectral anisotropy in b-tensor diffusion encoding using combined OGSE-STE waveforms at 15.2 T

Primary: Diffusion - Diffusion Acquisition
Secondary: Diffusion - Microstructure
667-02-001 · Diffusion Microstructure and Beyond · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row H
Keywords: Frequency-dependent diffusion MRI Tensor-valued Diffusion Encoding Diffusion Microstructure Oscillating gradient spin-echo (OGSE) Microscopic Anisotropy
Accepted
Jake Hamilton 1,2, Ricardo Rios-Carrillo1, Sam Laxer1,2, Ravi Menon1,2, Arthur Brown3,4, Corey A Baron1,2
1Centre for Functional and Metabolic Mapping, Robarts Research Institute - Western University, Canada
2Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, Canada
3Translational Neuroscience Group, Robarts Research Institute - Western University, Canada
4Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, Canada
Presenting Author: Jake Hamilton

Synopsis

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References

1. Basser PJ, Mattiello J, Lebihan D. Estimation of the Effective Self-Diffusion Tensor from the NMR Spin Echo. J Magn Reson B. 1994;103(3):247-254. doi:10.1006/jmrb.1994.1037 [doi]
2. Jensen JH, Helpern JA, Ramani A, Lu H, Kaczynski K. Diffusional kurtosis imaging: The quantification of non-gaussian water diffusion by means of magnetic resonance imaging. Magn Reson Med. 2005;53(6):1432-1440. doi:10.1002/mrm.20508 [doi]
3. Schachter M, Does MD, Anderson AW, Gore JC. Measurements of Restricted Diffusion Using an Oscillating Gradient Spin-Echo Sequence. Journal of Magnetic Resonance. 2000;147(2):232-237. doi:10.1006/jmre.2000.2203 [doi]
4. Lasič S, Szczepankiewicz F, Eriksson S, Nilsson M, Topgaard D. Microanisotropy imaging: quantification of microscopic diffusion anisotropy and orientational order parameter by diffusion MRI with magic-angle spinning of the q-vector. Front Phys. 2014;2. doi:10.3389/fphy.2014.00011 [doi]
5. Lasič S, Just N, Nilsson M, Szczepankiewicz F, Budde M, Lundell H. Spectral principal axis system (SPAS) and tuning of tensor-valued encoding for microscopic anisotropy and time-dependent diffusion in the rat brain. Imaging Neuroscience. 2025;3. doi:10.1162/IMAG.a.35 [doi]
6. Aggarwal M, Jantzie L. Disentangling microscopic anisotropy and diffusion time dependence in the brain using oscillating gradients with spherical b-tensor encoding. Annual Meeting of Intl Soc Mag Reson Med. Published online 2025.
7. Chen J, Ades-Aron B, Lee HH, et al. Optimization and validation of the DESIGNER preprocessing pipeline for clinical diffusion MRI in white matter aging. Imaging Neuroscience. 2024;2:1-17. doi:10.1162/imag_a_00125 [doi]
8. Arezza NJJ, Tse DHY, Baron CA. Rapid microscopic fractional anisotropy imaging via an optimized linear regression formulation. Magn Reson Imaging. 2021;80:132-143. doi:10.1016/j.mri.2021.04.015 [doi]
9. Hamilton J, Xu K, Geremia N, et al. Robust frequency-dependent diffusional kurtosis computation using an efficient direction scheme, axisymmetric modelling, and spatial regularization. Imaging Neuroscience. 2024;2:1-22. doi:10.1162/imag_a_00055 [doi]
10. Aggarwal M, Smith MD, Calabresi PA. Diffusion‐time dependence of diffusional kurtosis in the mouse brain. Magn Reson Med. 2020;84(3):1564-1578. doi:10.1002/mrm.28189 [doi]
11. Jespersen SN. Isotropic sampling of tensor‐encoded diffusion MRI. Magn Reson Med. 2025;93(5):2040-2048. doi:10.1002/mrm.30404 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/667-02-001