Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-05-007 ISMRM Abstract

Highly Localised Frontal Lobe Phosphorous MR Spectroscopy at 7 Tesla using a Dual-Tuned 1H/31P Surface Coil

Primary: Physics & Engineering - RF Arrays & Systems
Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
362-05-007 · Spectroscopy and Spectroscopic Imaging: Neuro II · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row C
Keywords: RF Arrays & Systems Phosphorous Magnetic Resonance Spectroscopy RF Safety Electromagnetic simulations Ultra-high field (UHF) MRI
Accepted
Un Hou Chan 1,2, Jabrane Karkouri3,4, Antoine Naegel1,5, Marzena Wylezinska-Arridge6, David Leitão1,2, Sarah McElroy1,2,7, Thomas R Eykyn1, Chris Rodgers3,4, Alice Egerton8, Vicky J Goh1,9, Ozlem Ipek1,2
1Research Dept of Imaging, Physics & Engineering, King's College London, London, United Kingdom
2London Collaborative Ultra high field System (LoCUS), London, United Kingdom
3Department of clinical neurosciences, University of Cambridge, Cambridge, United Kingdom
4Wolfson Brain Imaging Center, University of Cambridge, Cambridge, United Kingdom
5Siemens Healthcare SAS, Courbevoie, France
6Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
7MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom
8Department of Psychosis Studies, Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, London, United Kingdom
9Department of Radiology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
Presenting Author: Un Hou Chan

Synopsis

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References

1. Ackerman JJ, Grove TH, Wong GG, Gadian DG, Radda GK. Mapping of metabolites in whole animals by 31P NMR using surface coils. Nature. 1980;283:167–70.
2. Bottomley PA, Charles HC, Roemer PB, Flamig D, Engeseth H, Edelstein WA, et al. Human in vivo phosphate metabolite imaging with 31P NMR. Magnetic resonance in medicine. 1988;7:319–36.
3. Lee B, Zhu X, Woo MK, Adriany G, Schillak S, Chen W. Interleaved 31P MRS imaging of human frontal and occipital lobes using dual RF coils in combination with single‐channel transmitter–receiver and dynamic B0 shimming. NMR Biomed. 2018;31:e3842.
4. Wang Z, Lin JC, Mao W, Liu W, Smith MB, Collins CM. SAR and temperature: simulations and comparison to regulatory limits for MRI. Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine. 2007;26:437–41.
5. Gosselin M, Neufeld E, Moser H, Huber E, Farcito S, Gerber L, et al. Development of a new generation of high-resolution anatomical models for medical device evaluation: the Virtual Population 3.0. Physics in Medicine & Biology. 2014;59:5287.
6. Rodgers CT, Clarke WT, Snyder C, Vaughan JT, Neubauer S, Robson MD. Human cardiac 31P magnetic resonance spectroscopy at 7 Tesla. Magnetic resonance in medicine. 2014;72:304–15.
7. Karkouri J, Watson W, Forner R, Weir‐McCall JR, Horn T, Hill M, et al. Regionally resolved cardiac metabolism using a dipole‐loop array coil for 7 T 31P‐MRSI. Magnetic Resonance in Medicine. 2025;94:480–96.
8. Ren J, Sherry AD, Malloy CR. 31P‐MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times. NMR Biomed. 2015;28:1455–62.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/362-05-007