Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
601-02-006 ISMRM Abstract

Short- and long-term changes in trunk muscle volume, quality, and strength after diet-induced weight loss in the LION study

Primary: Body - Body Composition
Secondary: Musculoskeletal - Muscle
601-02-006 · Muscle MRI in Health and Disease: From Standardization to Application · Thursday, 14 May, 1:40 PM–3:30 PM · Hall 1A
Keywords: Tissue Characterization Metabolic imaging Fat infiltration
Accepted
Daniela Junker1, Johannes Raspe2, Anna Reik3, Mingming Wu 1,4, Stella M Näbauer1, Florian Kreuzpointner5, Kathrin Schmalzl5, Marcus R Makowski1, Hans Hauner3,6, Fabian Stöcker5, Christina Holzapfel3,7, Dimitrios Karampinos1,8,9
1Department for Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine and Health, Munich, Germany
2Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital, Technical University of Munich (TUM), Munich, Germany
3Institute of Nutritional Medicine, Technical University of Munich, School of Medicine and Health, Munich, Germany
4Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany
5Prevention Centre, Department of Health and Sport Sciences, Technical University of Munich, School of Medicine and Health, Munich, Germany
6Else Kröner-Fresenius Center for Nutritional Medicine, Technical University of Munich, School of Medicine and Health, Munich, Germany
7Department of Nutritional, Food and Consumer Sciences, Fulda University of Applied Sciences, Fulda, Germany
8CIBM Center for Biomedical Imaging, Lausanne, Switzerland
9Laboratory of Magnetic Resonance Imaging Systems and Methods, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Presenting Author: Mingming Wu

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References

1. Madrid DA, Beavers KM, Walkup MP, Ambrosius WT, Rejeski WJ, Marsh AP, et al. Effect of exercise modality and weight loss on changes in muscle and bone quality in older adults with obesity. Exp Gerontol. 2023;174:112126. doi:10.1016/j.exger.2023.112126. [doi]
2. Sollmann N, Zoffl A, Franz D, Syväri J, Dieckmeyer M, Burian E, et al. Regional variation in paraspinal muscle composition using chemical shift encoding-based water-fat MRI. Quant Imaging Med Surg. 2020;10(2):496–507. doi: 10.21037/qims.2020.01.10 [doi]
3. Gallagher D, Kelley DE, Thornton J, Boxt L, Pi-Sunyer FX, Lipkin E, et al. Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients. Am J Clin Nutr. 2017;105(1):78–84. doi:10.3945/ajcn.116.139188. [doi]
4. Reik A, Holzapfel C. Randomized Controlled Lifestyle Intervention (LION) Study for Weight Loss and Maintenance in Adults With Obesity-Design and Methods. Front Nutr. 2020;7:586985. doi: 10.3389/fnut.2020.586985 [doi]
5. Isensee F, Jaeger PF, Kohl SAA, Petersen J, Maier-Hein KH. nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat Methods. 2021;18(2):203-211
6. Somasundaram A, Wu M, Reik A, Rupp S, Han J, Näbauer S, et al. Evaluating sex-specific differences in abdominal fat volume and proton density fat fraction at MRI using automated nnU-Net-based segmentation. Radiol Artif Intell. 2024;6(4):e230471. doi: 10.1148/ryai.230471 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/601-02-006