Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
367-05-010 ISMRM Abstract

Rapid magnetization transfer imaging for ultra high field (UHF) MRI

Primary: Neuro - Multiple Sclerosis
Secondary: Acquisition & Reconstruction - Pulse Sequence Design: Neuro
367-05-010 · Neuroinflammation: Myelin and Iron · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row H
Keywords: Magnetization transfer MRI Ultra high field MRI Quantitative Magnetization Transfer Neuromelanin-Sensitive MRI 7T MRI
Accepted
Se-Hong Oh1,2, Ken Sakaie 2,3, Gawon Lee1, Devon S Conway4, Sarah M Planchon4, Daniel Ontaneda4, Stephen E Jones2,5, Mark Lowe2,3,5,6
1Department of Biomedical Engineering, Hankuk university of Foreign Studies, gyeonggi-do, Korea, Republic of
2Diagnostic Radiology, Cleveland Clinic, Cleveland, United States of America
3Cleveland Clinic, Cleveland, United States of America
4Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute, Cleveland Clinic, Cleveland, United States of America
5Imaging Institute, Cleveland Clinic, Cleveland, United States of America
6Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, United States of America
Presenting Author: Ken Sakaie

Synopsis

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References

1. Henkelman RM, Stanisz GJ, Graham SJ. Magnetization transfer in MRI: a review. NMR Biomed. 2001;14:57–64.
2. Sasaki M et al. Neuromelanin MR imaging of the substantia nigra and locus coeruleus. Nat Commun. 2021;12:2562.
3. Pike GB. Pulsed magnetization transfer contrast in gradient echo imaging. Magn Reson Med. 1996;36(1):95–103.
4. Sled JG. Modelling and interpretation of magnetization transfer imaging in the brain. NeuroImage. 2018;182:128–135.
5. Pohmann R et al. Quantitative MRI at 7 T and beyond: challenges and opportunities. Magn Reson Mater Phy. 2016;29:83–102.
6. Christodoulou AG et al. SAR management for quantitative MRI at 7 T. J Magn Reson Imaging. 2022;55(2):367–379.
7. Oh SH, Shin W, Lee J, Lowe MJ. Variable density magnetization transfer (vdMT) imaging for 7T MR imaging. NeuroImage. 2018 Mar;168:242–249
8. Oh SH et al. Efficient whole-brain quantitative magnetization transfer imaging using variable-density MT pulses. NeuroImage. 2025 (in revision).
9. Cabana J-F, Gu Y, Boudreau M, Levesque IR, Atchia Y, Sled JG, et al. Quantitative magnetization transfer imaging made easy with qMTLab: Software for data simulation, analysis, and visualization. Concepts in Magnetic Resonance Part A. 2015;44A(5):263-77.
10. Karakuzu A, Boudreau M, Duval T, Boshkovski T, Leppert I, Cabana J-F, et al. qMRLab: Quantitative MRI analysis, under one umbrella. Journal of Open Source Software. 2020;5(53).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/367-05-010