Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
567-04-008 ISMRM Abstract

The changes in the gray matter volume of the thalamus, hippocampus and amygdala in classic trigeminal neuralgia.

Primary: Neuro - Gray Matter
Secondary: Neuro - Peripheral Nerves
567-04-008 · Quantitative and Multimodal MRI Biomarkers Across Neurologic and Systemic Disorders · Wednesday, 13 May, 2:35 PM–3:30 PM · Digital Posters Row H
Accepted
Danyang Wang1, jingqi Jiang1,2, Kai AI3, Jing Zhang 1,4
1Department of Magnetic Resonance, Lanzhou, China
2Lanzhou University Second Hospital, Lanzhou, China
3Department of Clinical and Technical Support, Philips Healthcare (Xi'an), Xi'an, China
4The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
Presenting Author: Jing Zhang

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References

1. Bora N, Parihar P, Raj N, Shetty N, Nunna B. A Systematic Review of the Role of Magnetic Resonance Imaging in the Diagnosis and Detection of Neurovascular Conflict in Patients With Trigeminal Neuralgia. Cureus. 2023 Sep 3;15(9):e44614. doi: 10.7759/cureus.44614. PMID: 37799230; PMCID: PMC10547583. [doi] [pmid]
2. Herber S, Zimmerman RS, Chen A, Yang M, Martinez F. Teflon Granuloma With Active Inflammation: A Cause of Recurrent Trigeminal Neuralgia After Microvascular Decompression: Imaging and Pathological Correlation. Clin Nucl Med. 2024 Dec 1;49(12):1105-1108. doi: 10.1097/RLU.0000000000005444. Epub 2024 Oct 15. PMID: 39479994. [doi] [pmid]
3. Shen S, Zheng H, Wang J, Guo W, Guo X, Ji H, Zhang S, Chen Y, Shi G. Gray matter volume reduction with different disease duration in trigeminal neuralgia. Neuroradiology. 2022 Feb;64(2):301-311. doi: 10.1007/s00234-021-02783-y. Epub 2021 Aug 28. Erratum in: Neuroradiology. 2022 Feb;64(2):423. doi: 10.1007/s00234-021-02876-8. PMID: 34453181; PMCID: PMC8397610. [doi] [pmid]
4. Nardoni L, Tullo MG, Stefano GD, Fiorelli M, Caramia F. Structural brain alterations and changes in resting-state functional connectivity in patients with trigeminal neuralgia: A meta-analysis. Neuroimage Clin. 2025;46:103759. doi: 10.1016/j.nicl.2025.103759. Epub 2025 Feb 27. PMID: 40086208; PMCID: PMC11954123. [doi] [pmid]
5. Yan J, Wang L, Pan L, Ye H, Zhu X, Feng Q, Wang H, Ding Z, Ge X. Altered trends of local brain function in classical trigeminal neuralgia patients after a single trigger pain. BMC Med Imaging. 2024 Mar 18;24(1):66. doi: 10.1186/s12880-024-01239-y. PMID: 38500069; PMCID: PMC10949736. [doi] [pmid]
6. Vaculik MF, Noorani A, Hung PS, Hodaie M. Selective hippocampal subfield volume reductions in classic trigeminal neuralgia. Neuroimage Clin. 2019;23:101911. doi: 10.1016/j.nicl.2019.101911. Epub 2019 Jun 26. PMID: 31491821; PMCID: PMC6616529. [doi] [pmid]
7. Zhang Y, Mao Z, Pan L, Ling Z, Liu X, Zhang J, Yu X. Dysregulation of Pain- and Emotion-Related Networks in Trigeminal Neuralgia. Front Hum Neurosci. 2018 Mar 20;12:107. doi: 10.3389/fnhum.2018.00107. PMID: 29662445; PMCID: PMC5890150. [doi] [pmid]
8. Iglesias JE, Insausti R, Lerma-Usabiaga G, Bocchetta M, Van Leemput K, Greve DN, van der Kouwe A; Alzheimer's Disease Neuroimaging Initiative; Fischl B, Caballero-Gaudes C, Paz-Alonso PM. A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology. Neuroimage. 2018 Dec;183:314-326. doi: 10.1016/j.neuroimage.2018.08.012. Epub 2018 Aug 17. PMID: 30121337; PMCID: PMC6215335. [doi] [pmid]
9. Iglesias JE, Van Leemput K, Augustinack J, Insausti R, Fischl B, Reuter M; Alzheimer's Disease Neuroimaging Initiative. Bayesian longitudinal segmentation of hippocampal substructures in brain MRI using subject-specific atlases. Neuroimage. 2016 Nov 1;141:542-555. doi: 10.1016/j.neuroimage.2016.07.020. Epub 2016 Jul 15. PMID: 27426838; PMCID: PMC5026967. [doi] [pmid]
10. Saygin ZM, Kliemann D, Iglesias JE, van der Kouwe AJW, Boyd E, Reuter M, Stevens A, Van Leemput K, McKee A, Frosch MP, Fischl B, Augustinack JC; Alzheimer's Disease Neuroimaging Initiative. High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas. Neuroimage. 2017 Jul 15;155:370-382. doi: 10.1016/j.neuroimage.2017.04.046. Epub 2017 May 4. PMID: 28479476; PMCID: PMC5557007. [doi] [pmid]
11. Gallay MN, Magara AE, Moser D, Kowalski M, Kaeser M, Jeanmonod D. Magnetic resonance-guided focused ultrasound central lateral thalamotomy against chronic and therapy-resistant neuropathic pain: retrospective long-term follow-up analysis of 63 interventions. J Neurosurg. 2023 Feb 24;139(3):615-624. doi: 10.3171/2023.1.JNS222879. PMID: 36840733. [doi] [pmid]
12. Abdallat M, Saryyeva A, Blahak C, Wolf ME, Weigel R, Loher TJ, Runge J, Heissler HE, Kinfe TM, Krauss JK. Centromedian-Parafascicular and Somatosensory Thalamic Deep Brain Stimulation for Treatment of Chronic Neuropathic Pain: A Contemporary Series of 40 Patients. Biomedicines. 2021 Jun 25;9(7):731. doi: 10.3390/biomedicines9070731. PMID: 34202202; PMCID: PMC8301341. [doi] [pmid]
13. Lovo EE, Torres B, Campos F, Caceros V, Reyes WA, Barahona KC, Cruz C, Arias J, Alho E, Contreras WO. Stereotactic Gamma Ray Radiosurgery to the Centromedian and Parafascicular Complex of the Thalamus for Trigeminal Neuralgia and Other Complex Pain Syndromes. Cureus. 2019 Dec 19;11(12):e6421. doi: 10.7759/cureus.6421. PMID: 31886103; PMCID: PMC6925372. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/567-04-008