408-04-008 ISMRM Abstract

Fast, reliable, and high-quality χ-separation via EPTI and MRF

Primary: Contrast Mechanisms - Susceptibility/QSM

Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI

408-04-008 · Quantitative Imaging: MR Fingerprinting · Tuesday, 12 May, 4:00 PM–5:50 PM · Meeting Room 1.60

Keywords: Magnetic Resoance Fingerprinting Quantitative Susceptibility Mapping (QSM) Susceptibility source separation EPTI

Accepted

Hwihun Jeong^1,2, Jongho Lee², Yogesh Rathi¹, Michael Zeineh³, May Htwe Han⁴, Kawin Setsompop^3,5,6, Nan Wang ³

¹Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, United States of America

²Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of

³Department of Radiology, Stanford University, Stanford, United States of America

⁴Department of Neurology and Neurological Sciences, Stanford University, Stanford, United States of America

⁵Stanford Medicine, Stanford, United States of America

⁶Electrical Engineering, Stanford University, Stanford, United States of America

Presenting Author: Nan Wang

Synopsis

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References

1. Shin, Hyeong-Geol, et al. "χ-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain." Neuroimage 240 (2021): 118371.

2. Liu, Tian, et al. "Calculation of susceptibility through multiple orientation sampling (COSMOS): a method for conditioning the inverse problem from measured magnetic field map to susceptibility source image in MRI." Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine 61.1 (2009): 196-204.

3. Kim, Minjun, et al. "χ‐sepnet: deep neural network for magnetic susceptibility source separation." Human Brain Mapping 46.2 (2025): e70136.

4. Wang, Fuyixue, et al. "Echo planar time‐resolved imaging (EPTI)." Magnetic resonance in medicine 81.6 (2019): 3599-3615.

5. Wang, Nan, et al. "Spherical echo‐planar time‐resolved imaging (sEPTI) for rapid 3D quantitative T 2* and susceptibility imaging." Magnetic resonance in medicine 93.1 (2025): 121-137.

6. Ma, Dan, et al. "Magnetic resonance fingerprinting." Nature 495.7440 (2013): 187-192.

7. Cao, Xiaozhi, et al. "DTI‐MR fingerprinting for rapid high‐resolution whole‐brain T1, T2, proton density, ADC, and fractional anisotropy mapping." Magnetic resonance in medicine 91.3 (2024): 987-1001.

8. Shin, Hyeong-Geol, et al. "chi-separation using multi-orientation data in invivo and exvivo brains: Visualization of histology up to the resolution of 350 μm." Proceedings of the 30th Annual ISMRM Meeting, London. Vol. 771. 2022.

9. Yablonskiy, Dmitriy A., et al. "Voxel spread function method for correction of magnetic field inhomogeneity effects in quantitative gradient‐echo‐based MRI." Magnetic resonance in medicine 70.5 (2013): 1283-1292.

10. Kim, Taechang, et al. "Vessel segmentation for χ‐separation in quantitative susceptibility mapping." Magnetic Resonance in Medicine (2025).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/408-04-008