Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
564-03-013 ISMRM Abstract

Regional Magnetization Transfer Ratio Analysis for Detecting Early Microstructural Damage in Degenerative Cervical Myelopathy

Primary: Neuro - Spinal Cord
Secondary: Brain Function and fMRI - fMRI Analysis
564-03-013 · fMRI: Development and Aging · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row E
Keywords: Biomarker Degenerative cervical myelopathy Magnetization Transfer Ratio Spinal cord microstructure Early diagnosis
Accepted
Longyu Deng 1, wei cui2, Xiangyu Tang3
1Tongji Hospital affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wu Han, China
2MRI Research, GE Healthcare, Beijing, China
3Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue #1095, Wuhan, China
Presenting Author: Longyu Deng

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References

1. Dijkman MD, van Bilsen MWT, Fehlings MG, Bartels RHMA. Long-term functional outcome of surgical treatment for degenerative cervical myelopathy. J Neurosurg Spine. 2021 Nov 26;36(5):830-840. doi: 10.3171/2021.8.SPINE21651. PMID: 34826817. [doi] [pmid]
2. Foong J, Symms MR, Barker GJ, Maier M, Woermann FG, Miller DH, Ron MA. Neuropathological abnormalities in schizophrenia: evidence from magnetization transfer imaging. Brain. 2001 May;124(Pt 5):882-92. doi: 10.1093/brain/124.5.882. PMID: 11335691. [doi] [pmid]
3. Foesleitner O, Sturm V, Hayes J, Weiler M, Sam G, Wildemann B, Wick W, Bendszus M, Heiland S, Jäger LB. Microstructural changes of peripheral nerves in early multiple sclerosis: A prospective magnetic resonance neurography study. Eur J Neurol. 2024 Feb;31(2):e16126. doi: 10.1111/ene.16126. Epub 2023 Nov 6. PMID: 37932921. [doi] [pmid]
4. Haynes G, Muhammad F, Weber KA 2nd, Khan AF, Hameed S, Shakir H, Van Hal M, Dickson D, Rohan M, Dhaher Y, Parrish T, Ding L, Smith ZA. Tract-specific magnetization transfer ratio provides insights into the severity of degenerative cervical myelopathy. Spinal Cord. 2024 Dec;62(12):700-707. doi: 10.1038/s41393-024-01036-y. Epub 2024 Oct 1. PMID: 39354176. [doi] [pmid]
5. Hopkins BS, Weber KA 2nd, Cloney MB, Paliwal M, Parrish TB, Smith ZA. Tract-Specific Volume Loss on 3T MRI in Patients With Cervical Spondylotic Myelopathy. Spine (Phila Pa 1976). 2018 Oct 15;43(20):E1204-E1209. doi: 10.1097/BRS.0000000000002667. PMID: 29649085. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/564-03-013