Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-04-009 ISMRM Abstract

Altered IVIM-FWI Metrics in Pediatric Hematologic Cancer Survivors and Their Relationship with Cognitive Deficits

Primary: Diffusion - IVIM
Secondary: Pediatrics - Cancer
566-04-009 · Predicting Neurologic Outcomes · Wednesday, 13 May, 2:35 PM–3:30 PM · Digital Posters Row G
Keywords: Pediatric Cancer IVIM Cognition Free Water Imaging
Accepted
Faye F McKenna 1, Shounak Nandi2,3, SIDDHARTH NAYAK4, Sonya Henry5, Roman Fleysher3,6,7, Tim Duong3
1Albert Einstein College of Medicine, Bronx, United States of America
2Radiology, Albert Einstein College of Medicine, Bronx, United States of America
3Department of Radiology, Gruss Magnetic Resonance Research Center, Albert Einstein College of Medicine, Bronx, United States of America
4Neurology, Albert Einstein College of Medicine, Bronx, United States of America
5Department of Radiology, Albert Einstein College of Medicine, Bronx, United States of America
6Department of Radiology, Columbia University Irving Medical Center, New York, United States of America
7Gruss Magnetic Resonance Research Center, Department of Radiology, Albert Einstein College of Medicine, Bronx, United States of America
Presenting Author: Faye F McKenna

Synopsis

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References

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2. 2. Lange M, Joly F, Vardy J, Ahles T, Dubois M, Tron L, et al. Cancer-related cognitive impairment: An update on state of the art, detection, and management strategies in cancer survivors. Annals of Oncology. 2019 Dec 1;30(12):1925–40.
3. 3. Aukema EJ, Caan MWA, Oudhuis N, Majoie CBLM, Vos FM, Reneman L, et al. White Matter Fractional Anisotropy Correlates With Speed of Processing and Motor Speed in Young Childhood Cancer Survivors. Int J Radiat Oncol Biol Phys. 2009;74(3):837–43.
4. 4. Marusak HA, Iadipaolo AS, Harper FW, Elrahal F, Taub JW, Goldberg E, et al. Neurodevelopmental consequences of pediatric cancer and its treatment: applying an early adversity framework to understanding cognitive, behavioral, and emotional outcomes. Neuropsychol Rev. 2018;28(2):123–75.
5. 5. Weintraub S, Dikmen SS, Heaton RK, Tulsky DS, Zelazo PD, Bauer PJ, et al. Cognition assessment using the NIH Toolbox. Neurology. 2013;80(11 Suppl 3).
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7. 7. Rydhög AS, Szczepankiewicz F, Wirestam R, Ahlgren A, Westin CF, Knutsson L, et al. Separating blood and water: Perfusion and free water elimination from diffusion MRI in the human brain. Neuroimage. 2017;156(1):423–34.
8. 8. McKenna F, Gupta P, Sui YV, Bertisch H, Gonen O, Goff D, et al. Microstructural and Microvascular Alterations in Psychotic Spectrum Disorders: A Three- Compartment Intravoxel Incoherent Imaging and Free Water Model. Schizophr Bull. 2022;49(6):1542–53.
9. 9. Jenkinson M, Beckmann CF, Behrens TE, Woolrich MW, Smith SM. Fsl. Neuroimage. 2012;62(2):782–90.
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Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/566-04-009