570-08-228 ISMRM Abstract

Effects of modifiable dementia risk factors on brain metabolism and structure through multimodal MRI in transgenic mice

Primary: Neuro - Dementia

Secondary: Preclinical Animal & in vitro MR - Small Animals

570-08-228 · Preclinical · Wednesday, 13 May, 4:00 PM–4:55 PM · Traditional Posters | Exhibition Hall

Keywords: Dementia MRS Diffusion Tensor Imaging Modifiable risk factors

Accepted

Gianmauro Palombelli¹, Valentina Zecca^1,2, Gabriele De Luca³, Valeria SImonelli³, Paola Piscopo³, Federica Perrone³, Alessio Crestini³, Laura Ricceri³, Nicola Vanacore³, ROSSELLA CANESE ¹

¹MRI Unit - Core facilities, Istituto Superiore di Sanità, Rome, Italy

²Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Rome, Italy

³Istituto Superiore di Sanità, Rome, Italy

Presenting Author: ROSSELLA CANESE

Synopsis

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References

1. Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission (2024). The Lancet, Vol. 404 No. 10452, P 572-628. doi:10.1016/S0140-6736(24)01296-0 [doi]

2. De Luca G, Russo MT, Degan P, Tiveron C, Zijno A, Meccia E, Ventura I, Mattei E, Nakabeppu Y, Crescenzi M, Pepponi R, Pezzola A, Popoli P, Bignami M. PLoS Genet 2008;4(11):e1000266. doi: 10.1371/journal.pgen.1000266 [doi]

3. De Luca G, Ventura I, Sanghez V, Russo MT, Ajmone-Cat MA, Cacci E, Martire A, Popoli P, Falcone G, Michelini F, Crescenzi M, Degan P, Minghetti L, Bignami M, Calamandrei G. Aging Cell 2013;12(4):695-705. doi: 10.1111/acel.12094 [doi]

4. Öz G, Deelchand DK, Wijnen JP, Mlynárik V, Xin L, Mekle R, Noeske R, Scheenen TWJ, Tkáč I; Experts' Working Group on Advanced Single Voxel 1H MRS. NMR Biomed. 2020 Jan 10:e4236. doi: 10.1002/nbm.4236 [doi]

5. Canese R, Zoratto F, Altabella L, Porcari P, Mercurio L, Laviola G, Adriani. Psychopharmacology 2015; 232(1):75-89 doi: 10.1007/s00213-014-3639-6. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/570-08-228